Ribotoxic Proteins, Known as Inhibitors of Protein Synthesis, from Mushrooms and Other Fungi According to Endo’s Fragment Detection

Ribotoxic Proteins, Known as Inhibitors of Protein Synthesis, from Mushrooms and Other Fungi According to Endo’s Fragment Detection

rRNA N-glycosylases (EC 3.2.2.22) remove a specific adenine (A<sub>4324</sub>, rat 28S rRNA) in the sarcin ricin loop (SRL) involved into ribosome interaction with elongation factors, causing the inhibition of translation, for which they are known as plant ‘ribosome inactivating proteins...

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Bibliographic Details
Main Authors: Nicola Landi, Hafiza Z. F. Hussain, Paolo V. Pedone, Sara Ragucci, Antimo Di Maro
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Toxins
Subjects:
β-fragment
Endo’s assay
enzymes
fungi
mushrooms
N-glycosylases
Online Access:https://www.mdpi.com/2072-6651/14/6/403

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