Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary?
This study reviewed the incidence of positive pre-ablative diagnostic scan after total thyroidectomy and the efficacy of the current ablative dose. The predictive factors for outcome using a standard ablative dose and postoperative complications of total thyroidectomy were also examined. Methods: Th...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2005-04-01
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| Series: | Asian Journal of Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1015958409602694 |
| _version_ | 1818279201849999360 |
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| author | Choon Meng Teoh Muhammad Rohaizak Kin Yoong Chan Ali Yaakub Jasmi |
| author_facet | Choon Meng Teoh Muhammad Rohaizak Kin Yoong Chan Ali Yaakub Jasmi |
| author_sort | Choon Meng Teoh |
| collection | DOAJ |
| description | This study reviewed the incidence of positive pre-ablative diagnostic scan after total thyroidectomy and the efficacy of the current ablative dose. The predictive factors for outcome using a standard ablative dose and postoperative complications of total thyroidectomy were also examined.
Methods: This was a retrospective review of patients referred for radioiodine ablation after total thyroidectomy between September 1997 and September 2001.
Results: Forty patients were included in this study, of whom 95% had a positive scan after total thyroidectomy. Of the 30 patients who underwent standard 80-mCi radioiodine ablation, 21 (70%) had successful single ablation while the remaining nine patients needed a higher ablative dose. There were no significant differences between patients who had successful ablation with the standard dose and those who did not in terms of tumour size, patient age, lymph node status and extra-thyroidal extension. Fifteen percent suffered from permanent hypoparathyroidism requiring calcium supplementation. Three patients had documented recurrent laryngeal nerve paralysis.
Conclusion: Bypassing the pre-ablative diagnostic scan is feasible. The present ablation dose of 80 mCi of radioiodine is effective. The relatively high postoperative morbidity after difficult total thyroidectomy suggests less aggressive excision and postoperative radioiodine ablation of the remnant tissue. |
| first_indexed | 2024-12-12T23:29:34Z |
| format | Article |
| id | doaj.art-db1d9d72219e4fe4a2cc53a8892e7c55 |
| institution | Directory Open Access Journal |
| issn | 1015-9584 |
| language | English |
| last_indexed | 2024-12-12T23:29:34Z |
| publishDate | 2005-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Surgery |
| spelling | doaj.art-db1d9d72219e4fe4a2cc53a8892e7c552022-12-22T00:07:52ZengElsevierAsian Journal of Surgery1015-95842005-04-01282909610.1016/S1015-9584(09)60269-4Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary?Choon Meng TeohMuhammad RohaizakKin Yoong ChanAli Yaakub JasmiThis study reviewed the incidence of positive pre-ablative diagnostic scan after total thyroidectomy and the efficacy of the current ablative dose. The predictive factors for outcome using a standard ablative dose and postoperative complications of total thyroidectomy were also examined. Methods: This was a retrospective review of patients referred for radioiodine ablation after total thyroidectomy between September 1997 and September 2001. Results: Forty patients were included in this study, of whom 95% had a positive scan after total thyroidectomy. Of the 30 patients who underwent standard 80-mCi radioiodine ablation, 21 (70%) had successful single ablation while the remaining nine patients needed a higher ablative dose. There were no significant differences between patients who had successful ablation with the standard dose and those who did not in terms of tumour size, patient age, lymph node status and extra-thyroidal extension. Fifteen percent suffered from permanent hypoparathyroidism requiring calcium supplementation. Three patients had documented recurrent laryngeal nerve paralysis. Conclusion: Bypassing the pre-ablative diagnostic scan is feasible. The present ablation dose of 80 mCi of radioiodine is effective. The relatively high postoperative morbidity after difficult total thyroidectomy suggests less aggressive excision and postoperative radioiodine ablation of the remnant tissue.http://www.sciencedirect.com/science/article/pii/S1015958409602694radioiodine ablationrecurrent laryngeal nervethyroid carcinomatotal thyroidectomy |
| spellingShingle | Choon Meng Teoh Muhammad Rohaizak Kin Yoong Chan Ali Yaakub Jasmi Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary? Asian Journal of Surgery radioiodine ablation recurrent laryngeal nerve thyroid carcinoma total thyroidectomy |
| title | Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary? |
| title_full | Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary? |
| title_fullStr | Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary? |
| title_full_unstemmed | Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary? |
| title_short | Pre-ablative Diagnostic Whole-body Scan Following Total Thyroidectomy for Well-differentiated Thyroid Cancer: Is It Necessary? |
| title_sort | pre ablative diagnostic whole body scan following total thyroidectomy for well differentiated thyroid cancer is it necessary |
| topic | radioiodine ablation recurrent laryngeal nerve thyroid carcinoma total thyroidectomy |
| url | http://www.sciencedirect.com/science/article/pii/S1015958409602694 |
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