Plasmonic Nanomaterials for Colorimetric Biosensing: A Review

In the last few decades, plasmonic colorimetric biosensors raised increasing interest in bioanalytics thanks to their cost-effectiveness, responsiveness, and simplicity as compared to conventional laboratory techniques. Potential high-throughput screening and easy-to-use assay procedures make them a...

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Main Authors: Adriano Acunzo, Emanuela Scardapane, Maria De Luca, Daniele Marra, Raffaele Velotta, Antonio Minopoli
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/10/4/136
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author Adriano Acunzo
Emanuela Scardapane
Maria De Luca
Daniele Marra
Raffaele Velotta
Antonio Minopoli
author_facet Adriano Acunzo
Emanuela Scardapane
Maria De Luca
Daniele Marra
Raffaele Velotta
Antonio Minopoli
author_sort Adriano Acunzo
collection DOAJ
description In the last few decades, plasmonic colorimetric biosensors raised increasing interest in bioanalytics thanks to their cost-effectiveness, responsiveness, and simplicity as compared to conventional laboratory techniques. Potential high-throughput screening and easy-to-use assay procedures make them also suitable for realizing point of care devices. Nevertheless, several challenges such as fabrication complexity, laborious biofunctionalization, and poor sensitivity compromise their technological transfer from research laboratories to industry and, hence, still hamper their adoption on large-scale. However, newly-developing plasmonic colorimetric biosensors boast impressive sensing performance in terms of sensitivity, dynamic range, limit of detection, reliability, and specificity thereby continuously encouraging further researches. In this review, recently reported plasmonic colorimetric biosensors are discussed with a focus on the following categories: (i) on-platform-based (localized surface plasmon resonance, coupled plasmon resonance and surface lattice resonance); (ii) colloid aggregation-based (label-based and label free); (iii) colloid non-aggregation-based (nanozyme, etching-based and growth-based).
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spelling doaj.art-db1f210bbbdc45f9bcb6fdf2e727d96a2023-12-01T01:16:39ZengMDPI AGChemosensors2227-90402022-04-0110413610.3390/chemosensors10040136Plasmonic Nanomaterials for Colorimetric Biosensing: A ReviewAdriano Acunzo0Emanuela Scardapane1Maria De Luca2Daniele Marra3Raffaele Velotta4Antonio Minopoli5Department of Physics, University of Naples “Federico II”, Via Cintia 26, 80126 Naples, ItalyDepartment of Physics, University of Naples “Federico II”, Via Cintia 26, 80126 Naples, ItalyDepartment of Physics, University of Naples “Federico II”, Via Cintia 26, 80126 Naples, ItalyDepartment of Physics, University of Naples “Federico II”, Via Cintia 26, 80126 Naples, ItalyDepartment of Physics, University of Naples “Federico II”, Via Cintia 26, 80126 Naples, ItalyMax Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstraße 108, 01307 Dresden, GermanyIn the last few decades, plasmonic colorimetric biosensors raised increasing interest in bioanalytics thanks to their cost-effectiveness, responsiveness, and simplicity as compared to conventional laboratory techniques. Potential high-throughput screening and easy-to-use assay procedures make them also suitable for realizing point of care devices. Nevertheless, several challenges such as fabrication complexity, laborious biofunctionalization, and poor sensitivity compromise their technological transfer from research laboratories to industry and, hence, still hamper their adoption on large-scale. However, newly-developing plasmonic colorimetric biosensors boast impressive sensing performance in terms of sensitivity, dynamic range, limit of detection, reliability, and specificity thereby continuously encouraging further researches. In this review, recently reported plasmonic colorimetric biosensors are discussed with a focus on the following categories: (i) on-platform-based (localized surface plasmon resonance, coupled plasmon resonance and surface lattice resonance); (ii) colloid aggregation-based (label-based and label free); (iii) colloid non-aggregation-based (nanozyme, etching-based and growth-based).https://www.mdpi.com/2227-9040/10/4/136colorimetric biosensorsplasmonicspoint-of-carenanostructured substratescolloidal solutionsnanozymes
spellingShingle Adriano Acunzo
Emanuela Scardapane
Maria De Luca
Daniele Marra
Raffaele Velotta
Antonio Minopoli
Plasmonic Nanomaterials for Colorimetric Biosensing: A Review
Chemosensors
colorimetric biosensors
plasmonics
point-of-care
nanostructured substrates
colloidal solutions
nanozymes
title Plasmonic Nanomaterials for Colorimetric Biosensing: A Review
title_full Plasmonic Nanomaterials for Colorimetric Biosensing: A Review
title_fullStr Plasmonic Nanomaterials for Colorimetric Biosensing: A Review
title_full_unstemmed Plasmonic Nanomaterials for Colorimetric Biosensing: A Review
title_short Plasmonic Nanomaterials for Colorimetric Biosensing: A Review
title_sort plasmonic nanomaterials for colorimetric biosensing a review
topic colorimetric biosensors
plasmonics
point-of-care
nanostructured substrates
colloidal solutions
nanozymes
url https://www.mdpi.com/2227-9040/10/4/136
work_keys_str_mv AT adrianoacunzo plasmonicnanomaterialsforcolorimetricbiosensingareview
AT emanuelascardapane plasmonicnanomaterialsforcolorimetricbiosensingareview
AT mariadeluca plasmonicnanomaterialsforcolorimetricbiosensingareview
AT danielemarra plasmonicnanomaterialsforcolorimetricbiosensingareview
AT raffaelevelotta plasmonicnanomaterialsforcolorimetricbiosensingareview
AT antoniominopoli plasmonicnanomaterialsforcolorimetricbiosensingareview