GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons.

GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons.

Deficits in fast-spiking inhibitory interneurons (FSINs) within the dorsolateral prefrontal cortex (dlPFC) are hypothesized to underlie cognitive impairment associated with schizophrenia. Though representing a minority of interneurons, this key cell type coordinates broad neural network gamma-freque...

Full description

Bibliographic Details
Main Authors: Jonathan Garst-Orozco, Ruchi Malik, Thomas A Lanz, Mark L Weber, Hualin Xi, Dominique Arion, John F Enwright, David A Lewis, Patricio O'Donnell, Vikaas S Sohal, Derek L Buhl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0233895

Similar Items

Similar Items