Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534.
Asymptomatic bacteriuria is frequently detected in women aged up to 60 years, patients with diabetes and elderly patients. The benefit of antibiotic treatment for this condition is controversial. The objective of this Cochrane systematic review was to assess the effectiveness and safety of antibioti...
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| Format: | Article |
| Language: | English |
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Ordem dos Médicos
2018-02-01
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| Series: | Acta Médica Portuguesa |
| Subjects: | |
| Online Access: | https://actamedicaportuguesa.com/revista/index.php/amp/article/view/10077 |
| _version_ | 1818957912916099072 |
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| author | Miguel Bigotte Vieira Mariana Alves João Costa António Vaz-Carneiro |
| author_facet | Miguel Bigotte Vieira Mariana Alves João Costa António Vaz-Carneiro |
| author_sort | Miguel Bigotte Vieira |
| collection | DOAJ |
| description | Asymptomatic bacteriuria is frequently detected in women aged up to 60 years, patients with diabetes and elderly patients. The benefit of antibiotic treatment for this condition is controversial. The objective of this Cochrane systematic review was to assess the effectiveness and safety of antibiotic treatment for asymptomatic bacteriuria in adults. A systematic review of the literature up to 24 February 2015 was performed using the Cochrane Renal Group’s Specialised Register. Randomised controlled trials (RCTs) and quasirandomised controlled trials comparing antibiotics to placebo or no treatment for asymptomatic bacteriuria in adults were included. The outcomes of interest were the development of symptomatic urinary tract infection, complications, death, adverse events, development of antibiotic resistance, bacteriological cure, and decline in kidney function. Nine studies (1614 participants) were included in this review. The incidence of symptomatic urinary tract infection, complications or death was similar between groups. Antibiotic use was significantly associated with bacteriological cure and an increase in minor adverse events. No decline in kidney function was observed with any one of the treatments. According to the results of the studies included in this revision, authors have concluded that there is no clinical benefit in treating asymptomatic bacteriuria in adults. |
| first_indexed | 2024-12-20T11:17:24Z |
| format | Article |
| id | doaj.art-db2020e936e9411ba7af3de5412ab86c |
| institution | Directory Open Access Journal |
| issn | 0870-399X 1646-0758 |
| language | English |
| last_indexed | 2024-12-20T11:17:24Z |
| publishDate | 2018-02-01 |
| publisher | Ordem dos Médicos |
| record_format | Article |
| series | Acta Médica Portuguesa |
| spelling | doaj.art-db2020e936e9411ba7af3de5412ab86c2022-12-21T19:42:34ZengOrdem dos MédicosActa Médica Portuguesa0870-399X1646-07582018-02-01312767910.20344/amp.100774649Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534.Miguel Bigotte Vieira0Mariana Alves1João Costa2António Vaz-Carneiro3Co-primeiro autor. Serviço de Nefrologia e Transplantação Renal. Centro Hospitalar Lisboa Norte. Lisboa.Co-primeiro autor. Serviço de Medicina III. Centro Hospitalar Lisboa Norte. Lisboa. Instituto de Semiótica Clínica. Faculdade de Medicina. Universidade de Lisboa. Lisboa.Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Cochrane Portugal. Lisboa.Centro de Estudos de Medicina Baseada na Evidência. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Cochrane Portugal. Lisboa.Asymptomatic bacteriuria is frequently detected in women aged up to 60 years, patients with diabetes and elderly patients. The benefit of antibiotic treatment for this condition is controversial. The objective of this Cochrane systematic review was to assess the effectiveness and safety of antibiotic treatment for asymptomatic bacteriuria in adults. A systematic review of the literature up to 24 February 2015 was performed using the Cochrane Renal Group’s Specialised Register. Randomised controlled trials (RCTs) and quasirandomised controlled trials comparing antibiotics to placebo or no treatment for asymptomatic bacteriuria in adults were included. The outcomes of interest were the development of symptomatic urinary tract infection, complications, death, adverse events, development of antibiotic resistance, bacteriological cure, and decline in kidney function. Nine studies (1614 participants) were included in this review. The incidence of symptomatic urinary tract infection, complications or death was similar between groups. Antibiotic use was significantly associated with bacteriological cure and an increase in minor adverse events. No decline in kidney function was observed with any one of the treatments. According to the results of the studies included in this revision, authors have concluded that there is no clinical benefit in treating asymptomatic bacteriuria in adults.https://actamedicaportuguesa.com/revista/index.php/amp/article/view/10077AdultoAntibióticosBacteriúriaInfecções AssintomáticasRevisão sistemática |
| spellingShingle | Miguel Bigotte Vieira Mariana Alves João Costa António Vaz-Carneiro Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534. Acta Médica Portuguesa Adulto Antibióticos Bacteriúria Infecções Assintomáticas Revisão sistemática |
| title | Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534. |
| title_full | Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534. |
| title_fullStr | Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534. |
| title_full_unstemmed | Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534. |
| title_short | Bacteriuria. Cochrane Database Syst Rev. 2015;4:CD009534. |
| title_sort | bacteriuria cochrane database syst rev 2015 4 cd009534 |
| topic | Adulto Antibióticos Bacteriúria Infecções Assintomáticas Revisão sistemática |
| url | https://actamedicaportuguesa.com/revista/index.php/amp/article/view/10077 |
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