Human cytomegalovirus vaccine based on the envelope gH/gL pentamer complex.

Human Cytomegalovirus (HCMV) utilizes two different pathways for host cell entry. HCMV entry into fibroblasts requires glycoproteins gB and gH/gL, whereas HCMV entry into epithelial and endothelial cells (EC) requires an additional complex composed of gH, gL, UL128, UL130, and UL131A, referred to as...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Felix Wussow, Flavia Chiuppesi, Joy Martinez, John Campo, Erica Johnson, Christin Flechsig, Maegan Newell, Elaine Tran, Jose Ortiz, Corinna La Rosa, Andreas Herrmann, Jeff Longmate, Rana Chakraborty, Peter A Barry, Don J Diamond
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Public Library of Science (PLoS) 2014-11-01
Σειρά:PLoS Pathogens
Διαθέσιμο Online:http://europepmc.org/articles/PMC4239111?pdf=render