Glioblastoma extracellular vesicles modulate immune PD-L1 expression in accessory macrophages upon radiotherapy

Glioblastoma extracellular vesicles modulate immune PD-L1 expression in accessory macrophages upon radiotherapy

Summary: Glioblastoma (GBM) is the most aggressive brain tumor, presenting major challenges due to limited treatment options. Standard care includes radiation therapy (RT) to curb tumor growth and alleviate symptoms, but its impact on GBM is limited. In this study, we investigated the effect of RT o...

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Bibliographic Details
Main Authors: Markus W. Schweiger, Zohreh Amoozgar, Pierre Repiton, Robert Morris, Semer Maksoud, Michael Hla, Eric Zaniewski, David P. Noske, Wilhelm Haas, Koen Breyne, Bakhos A. Tannous
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Immunology
Cell biology
Cancer
Proteomics
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224000282

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