Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal
Presently we report a second example of a biochemical reaction sensitized remotely by excitons (electronic excited states) efficiently transferred along intermediate filaments (IFs) over macroscopic distances. IFs are excellent conductors of energy in the form of excitons, with the efficiency of ca....
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| Format: | Article |
| Language: | English |
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Elsevier
2023-10-01
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| Series: | Journal of Photochemistry and Photobiology |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S266646902300043X |
| _version_ | 1797682835568459776 |
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| author | Igor Khmelinskii Vladimir Makarov |
| author_facet | Igor Khmelinskii Vladimir Makarov |
| author_sort | Igor Khmelinskii |
| collection | DOAJ |
| description | Presently we report a second example of a biochemical reaction sensitized remotely by excitons (electronic excited states) efficiently transferred along intermediate filaments (IFs) over macroscopic distances. IFs are excellent conductors of energy in the form of excitons, with the efficiency of ca. 0.53 reported in vitro. Excitons were generated by visible light and propagated along Müller cell (MC) intermediate filaments, about 100 μm long. These experiments used a capillary matrix filled by MC IFs extracted from porcine retina. Excitons induced efficient isomerization of 11-cis- to all-trans-retinal, with the reaction quantum yield φcis/trans = 0.347 obtained for 11-cis-retinal concentration of 1.0 × 10−3 M (0.284 g/L) using 546 nm light at 6.87 mW/cm2 power density. Exciton quantum yield φexc at 546 nm was also measured in function of radiation power density, with nonlinearity indicative of biphotonic processes. This is the first case of biphotonic processes occurring at such low light intensities with steady-state illumination. The present results support quantum mechanism of high-contrast vision of vertebrate eyes. |
| first_indexed | 2024-03-12T00:05:38Z |
| format | Article |
| id | doaj.art-db279e6ef20449feabf67649fdb8ee4a |
| institution | Directory Open Access Journal |
| issn | 2666-4690 |
| language | English |
| last_indexed | 2024-03-12T00:05:38Z |
| publishDate | 2023-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Photochemistry and Photobiology |
| spelling | doaj.art-db279e6ef20449feabf67649fdb8ee4a2023-09-17T04:57:35ZengElsevierJournal of Photochemistry and Photobiology2666-46902023-10-0117100202Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinalIgor Khmelinskii0Vladimir Makarov1Universidade do Algarve, FCT, DQB and CEOT, 8005-139, Faro, Portugal; Corresponding author.University of Puerto Rico, Rio Piedras Campus, PO Box 23343, San Juan, PR 00931-3343, United States of AmericaPresently we report a second example of a biochemical reaction sensitized remotely by excitons (electronic excited states) efficiently transferred along intermediate filaments (IFs) over macroscopic distances. IFs are excellent conductors of energy in the form of excitons, with the efficiency of ca. 0.53 reported in vitro. Excitons were generated by visible light and propagated along Müller cell (MC) intermediate filaments, about 100 μm long. These experiments used a capillary matrix filled by MC IFs extracted from porcine retina. Excitons induced efficient isomerization of 11-cis- to all-trans-retinal, with the reaction quantum yield φcis/trans = 0.347 obtained for 11-cis-retinal concentration of 1.0 × 10−3 M (0.284 g/L) using 546 nm light at 6.87 mW/cm2 power density. Exciton quantum yield φexc at 546 nm was also measured in function of radiation power density, with nonlinearity indicative of biphotonic processes. This is the first case of biphotonic processes occurring at such low light intensities with steady-state illumination. The present results support quantum mechanism of high-contrast vision of vertebrate eyes.http://www.sciencedirect.com/science/article/pii/S266646902300043XExcitonsLong-range energy transferIntermediate filamentsPhysical signaling within cellsPhysical signaling between cellsIntermediate filament excitons |
| spellingShingle | Igor Khmelinskii Vladimir Makarov Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal Journal of Photochemistry and Photobiology Excitons Long-range energy transfer Intermediate filaments Physical signaling within cells Physical signaling between cells Intermediate filament excitons |
| title | Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal |
| title_full | Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal |
| title_fullStr | Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal |
| title_full_unstemmed | Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal |
| title_short | Biochemical reactions remote-sensitized by excitons propagating across macroscopic distances along biological fibers: Isomerization of 11-cis-retinal |
| title_sort | biochemical reactions remote sensitized by excitons propagating across macroscopic distances along biological fibers isomerization of 11 cis retinal |
| topic | Excitons Long-range energy transfer Intermediate filaments Physical signaling within cells Physical signaling between cells Intermediate filament excitons |
| url | http://www.sciencedirect.com/science/article/pii/S266646902300043X |
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