Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspective
Objectives: This study aimed to simulate blood flow stagnation using computational fluid dynamics and to clarify the optimal design of segmental artery reattachment for thoracoabdominal aortic repair. Methods: Blood flow stagnation, defined by low-velocity volume or area of the segmental artery, was...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-09-01
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| Series: | JTCVS Open |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666273623001936 |
| _version_ | 1797674169323749376 |
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| author | Yuki Ikeno, MD, PhD Yoshishige Takayama, MEng Michael L. Williams, MD Yujiro Kawaniashi, MD, PhD Paul Jansz, MD, PhD |
| author_facet | Yuki Ikeno, MD, PhD Yoshishige Takayama, MEng Michael L. Williams, MD Yujiro Kawaniashi, MD, PhD Paul Jansz, MD, PhD |
| author_sort | Yuki Ikeno, MD, PhD |
| collection | DOAJ |
| description | Objectives: This study aimed to simulate blood flow stagnation using computational fluid dynamics and to clarify the optimal design of segmental artery reattachment for thoracoabdominal aortic repair. Methods: Blood flow stagnation, defined by low-velocity volume or area of the segmental artery, was simulated by a 3-dimensional model emulating the systolic phase. Four groups were evaluated: direct anastomosis, graft interposition, loop-graft, and end graft. Based on contemporary clinical studies, direct anastomosis can provide a superior patency rate than other reattachment methods. We hypothesized that stagnation of the blood flow is negatively associated with patency rates. Over time, velocity changes were evaluated. Results: The direct anastomosis method led to the least blood flow stagnation, whilst the end-graft reattachment method resulted in worse blood flow stagnation. The loop-graft method was comparatively during late systole, which was also influenced by configuration of the side branch. Graft interposition using 20 mm showed a low-velocity area in the distal part of the side graft. When comparing length and diameter of an interposed graft, shorter and smaller branches resulted in less blood flow stagnation. Conclusions: In our simulation, direct anastomosis of the segmental artery resulted in the most efficient design in terms of blood flow stagnation. A shorter (<20 mm) and smaller (<10 mm) branch should be used for graft interposition. Loop-graft is an attractive alternative to direct anastomosis; however, its blood flow pattern can be influenced. |
| first_indexed | 2024-03-11T21:55:11Z |
| format | Article |
| id | doaj.art-db295518f1224b7db85c5be60e201d97 |
| institution | Directory Open Access Journal |
| issn | 2666-2736 |
| language | English |
| last_indexed | 2024-03-11T21:55:11Z |
| publishDate | 2023-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JTCVS Open |
| spelling | doaj.art-db295518f1224b7db85c5be60e201d972023-09-26T04:12:36ZengElsevierJTCVS Open2666-27362023-09-01156171Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspectiveYuki Ikeno, MD, PhD0Yoshishige Takayama, MEng1Michael L. Williams, MD2Yujiro Kawaniashi, MD, PhD3Paul Jansz, MD, PhD4Department of Cardiothoracic Surgery, St Vincent Hospital Sydney, Sydney, New South Wales, Australia; Address for reprints: Yuki Ikeno, MD, PhD, Department of Cardiothoracic Surgery, St Vincent's Hospital Sydney, 390 Victoria St, Darlinghust, Sydney, New South Wales 2010, Australia.Division of Simcenter Support, Department of CCM, Siemens K.K., Tokyo, JapanDepartment of Cardiothoracic Surgery, St Vincent Hospital Sydney, Sydney, New South Wales, AustraliaDepartment of Cardiothoracic Surgery, St Vincent Hospital Sydney, Sydney, New South Wales, AustraliaDepartment of Cardiothoracic Surgery, St Vincent Hospital Sydney, Sydney, New South Wales, AustraliaObjectives: This study aimed to simulate blood flow stagnation using computational fluid dynamics and to clarify the optimal design of segmental artery reattachment for thoracoabdominal aortic repair. Methods: Blood flow stagnation, defined by low-velocity volume or area of the segmental artery, was simulated by a 3-dimensional model emulating the systolic phase. Four groups were evaluated: direct anastomosis, graft interposition, loop-graft, and end graft. Based on contemporary clinical studies, direct anastomosis can provide a superior patency rate than other reattachment methods. We hypothesized that stagnation of the blood flow is negatively associated with patency rates. Over time, velocity changes were evaluated. Results: The direct anastomosis method led to the least blood flow stagnation, whilst the end-graft reattachment method resulted in worse blood flow stagnation. The loop-graft method was comparatively during late systole, which was also influenced by configuration of the side branch. Graft interposition using 20 mm showed a low-velocity area in the distal part of the side graft. When comparing length and diameter of an interposed graft, shorter and smaller branches resulted in less blood flow stagnation. Conclusions: In our simulation, direct anastomosis of the segmental artery resulted in the most efficient design in terms of blood flow stagnation. A shorter (<20 mm) and smaller (<10 mm) branch should be used for graft interposition. Loop-graft is an attractive alternative to direct anastomosis; however, its blood flow pattern can be influenced.http://www.sciencedirect.com/science/article/pii/S2666273623001936basic sciencecomputational fluid dynamicsspinal cord injurythoracoabdominal aortic aneurysm repair |
| spellingShingle | Yuki Ikeno, MD, PhD Yoshishige Takayama, MEng Michael L. Williams, MD Yujiro Kawaniashi, MD, PhD Paul Jansz, MD, PhD Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspective JTCVS Open basic science computational fluid dynamics spinal cord injury thoracoabdominal aortic aneurysm repair |
| title | Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspective |
| title_full | Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspective |
| title_fullStr | Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspective |
| title_full_unstemmed | Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspective |
| title_short | Computational fluid dynamics simulate optimal design of segmental arteries reattachment: Influence of blood flow stagnationCentral MessagePerspective |
| title_sort | computational fluid dynamics simulate optimal design of segmental arteries reattachment influence of blood flow stagnationcentral messageperspective |
| topic | basic science computational fluid dynamics spinal cord injury thoracoabdominal aortic aneurysm repair |
| url | http://www.sciencedirect.com/science/article/pii/S2666273623001936 |
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