A Tandem Oligonucleotide Approach for SNP-Selective RNA Degradation Using Modified Antisense Oligonucleotides.

A Tandem Oligonucleotide Approach for SNP-Selective RNA Degradation Using Modified Antisense Oligonucleotides.

Antisense oligonucleotides have been studied for many years as a tool for gene silencing. One of the most difficult cases of selective RNA silencing involves the alleles of single nucleotide polymorphisms, in which the allele sequence is differentiated by a single nucleotide. A new approach to impro...

Descripción completa

Detalles Bibliográficos
Autores principales: Dorota Magner, Ewa Biala, Jolanta Lisowiec-Wachnicka, Elzbieta Kierzek, Ryszard Kierzek
Formato: Artículo
Lenguaje:English
Publicado: Public Library of Science (PLoS) 2015-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC4704561?pdf=render

Ejemplares similares

Ejemplares similares