Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-γ stimulated macrophages

Azithromycin suppresses interleukin-12p40 expression in lipopolysaccharide and interferon-γ stimulated macrophages

<p>Azithromycin (AZM), a 15-member macrolide antibiotic, possesses anti-inflammatory activity. Macrophages are important in innate and acquired immunity, and produce pro-inflammatory cytokines such as interleukin (IL)-12, which are composed of subunit p40 and p35. The key function of IL-12 is...

Full description

Bibliographic Details
Main Author:	Keiko Yamauchi, Yoko Shibata, Tomomi Kimura, Shuichi Abe, Sumito Inoue, Daisuke Osaka, Michiko Sato, Akira Igarashi, Isao Kubota
Format:	Article
Language:	English
Published:	Ivyspring International Publisher 2009-01-01
Series:	International Journal of Biological Sciences
Online Access:	http://www.biolsci.org/v05p0667.htm

Similar Items

Reduced number and morphofunctional change of alveolar macrophages in MafB gene-targeted mice.
by: Michiko Sato-Nishiwaki, et al.
Published: (2013-01-01)

Relationships between values of antibodies to several connective tissue disease autoantigens and pulmonary function in a Japanese general population: the Takahata study.
by: Hiroshi Nakano, et al.
Published: (2013-01-01)

Impairment of Pulmonary Function is an Independent Risk Factor for Atrial Fibrillation: The Takahata Study
by: Yoko Shibata, Tetsu Watanabe, Daisuke Osaka, Shuichi Abe, Sumito Inoue, Yoshikane Tokairin, Akira Igarashi, Keiko Yamauchi, Tomomi Kimura, Hiroyuki Kishi, Yasuko Aida, Keiko Nunomiya, Takako Nemoto, Masamichi Sato, Tsuneo Konta, Sumio Kawata, Takeo Kato,
Published: (2011-01-01)

A lower level of forced expiratory volume in 1 second is a risk factor for all-cause and cardiovascular mortality in a Japanese population: the Takahata study.
by: Yoko Shibata, et al.
Published: (2013-01-01)

Elevated serum iron is a potent biomarker for spirometric resistance to cigarette smoke among Japanese males: the Takahata study.
by: Yoko Shibata, et al.
Published: (2013-01-01)

Retrospective Analysis of the Relationship between Decline in FEV1 and Abdominal Circumference in Male Smokers: the Takahata Study
by: Masamichi Sato, Yoko Shibata, Shuichi Abe, Sumito Inoue, Akira Igarashi, Keiko Yamauchi, Yasuko Aida, Hiroyuki Kishi, Keiko Nunomiya, Hiroshi Nakano, Kento Sato, Tetsu Watanabe, Tsuneo Konta, Yoshiyuki Ueno, Takeo Kato, Takamasa Kayama, Isao Kubota
Published: (2013-01-01)

Thymus and activation-regulated chemokine (TARC/CCL17) predicts decline of pulmonary function in patients with chronic obstructive pulmonary disease
by: Hiroyoshi Machida, et al.
Published: (2021-01-01)

Acetoxy-γ-valerolactone
by: Cameron Tristram, et al.
Published: (2013-06-01)

Estratégias para a síntese de γ-alquilidenobutenolídeos Strategies for the synthesis of γ-alkilidenebutenolides
by: Luiz Cláudio Almeida Barbosa, et al.
Published: (2010-01-01)

Effect of hyperhomocysteinemia on a murine model of smoke-induced pulmonary emphysema
by: Hiroshi Nakano, et al.
Published: (2022-07-01)

Interferon-tau attenuates uptake of nanoparticles and secretion of interleukin-1β in macrophages.
by: Kyoko Hara, et al.
Published: (2014-01-01)

Extraction of &#947-oryzanol from rice bran Extração de γ-oryzanol de farelo de arroz
by: Renata Heidtmann-Bemvenuti, et al.
Published: (2012-12-01)

The pharmacokinetic-pharmacodynamic model of azithromycin for lipopolysaccharide-induced depressive-like behavior in mice.
by: Kun Hao, et al.
Published: (2013-01-01)

The Effects of Pentoxifylline on Serum Levels of Interleukin 10 and Interferon Gamma and Memory Function in Lipopolysaccharide-induced Inflammation in Rats
by: Hamid Reza Dehghani Dolatabadi, et al.
Published: (2017-01-01)

Stimulation of bovine monocyte-derived macrophages with lipopolysaccharide, interferon-ɣ, Interleukin-4 or Interleukin-13 does not induce detectable changes in nitric oxide or arginase activity
by: Heather Imrie, et al.
Published: (2019-01-01)

Decreased Osteopontin Expression as a Reliable Prognostic Indicator of Improvement in Pulmonary Tuberculosis: Impact of the Level of Interferon-γ-Inducible Protein 10
by: Yunan Zhu, et al.
Published: (2015-11-01)

SPECTROPOLARIMETRY OF β Cephei TYPE STAR γ Pegasi
by: V. V. Butkovskaya
Published: (2017-04-01)

THE ABUNDANCES OF SOME HEAVY ELEMENTS IN THE ATMOSPHERE OF γ TAURI
by: A. V. Yushchenko, et al.
Published: (2017-07-01)

Azithromycin decreases Chlamydia pneumoniae-mediated Interleukin-4 responses but not Immunoglobulin E responses.
by: Tamar A Smith-Norowitz, et al.
Published: (2020-01-01)

Effect of incubation with lipopolysaccharide and interferon-γ on reactive astrogliosis
by: Xiaoli Hua, et al.
Published: (2019-12-01)

Dynamic dielectric properties and the γ transition of bromine doped polyacrylonitrile
Published: (2007-10-01)

LEI 11.947/2009, PNAE E AGRICULTURA FAMILIAR
by: Luís Fernando Silva Marques, et al.
Published: (2021-11-01)

Lack of Genetic Associations of PPAR-γ and PGC-1α with Alzheimer's Disease and Parkinson's Disease with Dementia
by: Nobuto Shibata, et al.
Published: (2013-05-01)

Interferon Regulatory Factor 5 Mediates Lipopolysaccharide-Induced Neuroinflammation
by: Ziqi Fan, et al.
Published: (2020-12-01)

Later Han Empire (947-979) - the Last Empire of Shatuo in China
by: A. G. Nesterov
Published: (2018-11-01)

Síntese e caracterização de óxido hidróxido de manganês do tipo manganita (γ -MnOOH) Synthesis and characterization of manganese oxyhydroxide manganite (γ -MnOOH) type
by: B. A. M. Figueira, et al.
Published: (2008-06-01)

Heterogeneidade de resposta por IFN-γ a cepas clínicas de Mycobacterium tuberculosis em humanos Heterogeneity in human IFN-γ responses to clinical Mycobacterium tuberculosis strains
by: Vinícius Ribeiro Cabral, et al.
Published: (2010-08-01)

Selective Up-regulation of P2X4-Receptor Gene Expression by Interferon-γ in Vascular Endothelial Cells
by: Yan Tang, et al.
Published: (2008-01-01)

The Story of Azithromycin
by: Banić Tomišić, Z.
Published: (2011-12-01)

Interleukin 4 induces interleukin 6 production by endothelial cells: synergy with interferon-gamma.
by: Howells, G, et al.
Published: (1991)

Patrones de uso de antihipertensivos en 11.947 pacientes colombianos.
by: Carlos A. Isaza, et al.
Published: (2002-12-01)

NEW PERIOD OF THE LONGITUDINAL MAGNETIC FIELD VARIABILITY IN Ap STAR γ EQU
by: V. D. Bychkov, et al.
Published: (2017-04-01)

Insilico Analysis of γ- Aminobutaric Acid Transaminase (GABA-T) of Brassica napus (Rape)
by: Md. Shahjahan, et al.
Published: (2019-04-01)

Diverse coactivator recruitment through differential PPARγ nuclear receptor agonism
by: Fernando Lizcano, et al.
Published: (2013-01-01)

Biotransformation of sucrose into 5-hydroxy-2-hydroxymethyl-γ-pirone by Aspergillus flavus
by: Nelson R. Ferreira, et al.
Published: (2010-09-01)

RAPID OSCILLATIONS IN THE SPECTRUM OF roAp STARS χ PSC AND γ EQU
by: S. G. Aliev, et al.
Published: (2017-04-01)

4,8-Dimethoxyfuro[2,3-b]quinoline (&#947;-fagarine)
by: Yong Liu, et al.
Published: (2011-08-01)

Localization of interferons and interleukin 2 in polymyositis and muscular dystrophy.
by: Isenberg, D, et al.
Published: (1986)

Antiviral Activities of Interleukin-27: A Partner for Interferons?
by: Heather Amsden, et al.
Published: (2022-05-01)

Effect of diarylpentanoid analogues on lipopolysaccharide-induced interleukin-6 and interleukin-8 gene expression in airway inflammation
by: Liew, Kong Yen, et al.
Published: (2019)