REverSe TRanscrIptase chain termination (RESTRICT) for selective measurement of nucleotide analogs used in HIV care and prevention

REverSe TRanscrIptase chain termination (RESTRICT) for selective measurement of nucleotide analogs used in HIV care and prevention

Abstract Sufficient drug concentrations are required for efficacy of antiretroviral drugs used in HIV care and prevention. Measurement of nucleotide analogs, included in most HIV medication regimens, enables monitoring of short‐ and long‐term adherence and the risk of treatment failure. The REverSe...

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Bibliographic Details
Main Authors: Ayokunle O. Olanrewaju, Benjamin P. Sullivan, Alicia H. Gim, Cosette A. Craig, Derin Sevenler, Andrew T. Bender, Paul K. Drain, Jonathan D. Posner
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Bioengineering & Translational Medicine
Subjects:
adherence monitoring
enzymatic assay
nucleotide analog
nucleotide reverse transcriptase inhibitor
reverse transcriptase inhibitor
tenofovir diphosphate
Online Access:https://doi.org/10.1002/btm2.10369

Internet

https://doi.org/10.1002/btm2.10369

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