Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.

INTRODUCTION:The Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument is the most commonly used guideline appraisal tool. It includes 23 appraisal criteria (items) organized within 6 domains and 2 overall assessments (1. overall guideline quality; 2. recommendation for use). T...

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Main Authors: Wiebke Hoffmann-Eßer, Ulrich Siering, Edmund A M Neugebauer, Anne Catharina Brockhaus, Ulrike Lampert, Michaela Eikermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5373625?pdf=render
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author Wiebke Hoffmann-Eßer
Ulrich Siering
Edmund A M Neugebauer
Anne Catharina Brockhaus
Ulrike Lampert
Michaela Eikermann
author_facet Wiebke Hoffmann-Eßer
Ulrich Siering
Edmund A M Neugebauer
Anne Catharina Brockhaus
Ulrike Lampert
Michaela Eikermann
author_sort Wiebke Hoffmann-Eßer
collection DOAJ
description INTRODUCTION:The Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument is the most commonly used guideline appraisal tool. It includes 23 appraisal criteria (items) organized within 6 domains and 2 overall assessments (1. overall guideline quality; 2. recommendation for use). The aim of this systematic review was twofold. Firstly, to investigate how often AGREE II users conduct the 2 overall assessments. Secondly, to investigate the influence of the 6 domain scores on each of the 2 overall assessments. MATERIALS AND METHODS:A systematic bibliographic search was conducted for publications reporting guideline appraisals with AGREE II. The impact of the 6 domain scores on the overall assessment of guideline quality was examined using a multiple linear regression model. Their impact on the recommendation for use (possible answers: "yes", "yes, with modifications", "no") was examined using a multinomial regression model. RESULTS:118 relevant publications including 1453 guidelines were identified. 77.1% of the publications reported results for at least one overall assessment, but only 32.2% reported results for both overall assessments. The results of the regression analyses showed a statistically significant influence of all domains on overall guideline quality, with Domain 3 (rigour of development) having the strongest influence. For the recommendation for use, the results showed a significant influence of Domains 3 to 5 ("yes" vs. "no") and Domains 3 and 5 ("yes, with modifications" vs. "no"). CONCLUSIONS:The 2 overall assessments of AGREE II are underreported by guideline assessors. Domains 3 and 5 have the strongest influence on the results of the 2 overall assessments, while the other domains have a varying influence. Within a normative approach, our findings could be used as guidance for weighting individual domains in AGREE II to make the overall assessments more objective. Alternatively, a stronger content analysis of the individual domains could clarify their importance in terms of guideline quality. Moreover, AGREE II should require users to transparently present how they conducted the assessments.
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spelling doaj.art-db37fc32497f481d8a6086d0f404cd6e2022-12-21T23:53:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01123e017483110.1371/journal.pone.0174831Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.Wiebke Hoffmann-EßerUlrich SieringEdmund A M NeugebauerAnne Catharina BrockhausUlrike LampertMichaela EikermannINTRODUCTION:The Appraisal of Guidelines for Research & Evaluation (AGREE) II instrument is the most commonly used guideline appraisal tool. It includes 23 appraisal criteria (items) organized within 6 domains and 2 overall assessments (1. overall guideline quality; 2. recommendation for use). The aim of this systematic review was twofold. Firstly, to investigate how often AGREE II users conduct the 2 overall assessments. Secondly, to investigate the influence of the 6 domain scores on each of the 2 overall assessments. MATERIALS AND METHODS:A systematic bibliographic search was conducted for publications reporting guideline appraisals with AGREE II. The impact of the 6 domain scores on the overall assessment of guideline quality was examined using a multiple linear regression model. Their impact on the recommendation for use (possible answers: "yes", "yes, with modifications", "no") was examined using a multinomial regression model. RESULTS:118 relevant publications including 1453 guidelines were identified. 77.1% of the publications reported results for at least one overall assessment, but only 32.2% reported results for both overall assessments. The results of the regression analyses showed a statistically significant influence of all domains on overall guideline quality, with Domain 3 (rigour of development) having the strongest influence. For the recommendation for use, the results showed a significant influence of Domains 3 to 5 ("yes" vs. "no") and Domains 3 and 5 ("yes, with modifications" vs. "no"). CONCLUSIONS:The 2 overall assessments of AGREE II are underreported by guideline assessors. Domains 3 and 5 have the strongest influence on the results of the 2 overall assessments, while the other domains have a varying influence. Within a normative approach, our findings could be used as guidance for weighting individual domains in AGREE II to make the overall assessments more objective. Alternatively, a stronger content analysis of the individual domains could clarify their importance in terms of guideline quality. Moreover, AGREE II should require users to transparently present how they conducted the assessments.http://europepmc.org/articles/PMC5373625?pdf=render
spellingShingle Wiebke Hoffmann-Eßer
Ulrich Siering
Edmund A M Neugebauer
Anne Catharina Brockhaus
Ulrike Lampert
Michaela Eikermann
Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
PLoS ONE
title Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
title_full Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
title_fullStr Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
title_full_unstemmed Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
title_short Guideline appraisal with AGREE II: Systematic review of the current evidence on how users handle the 2 overall assessments.
title_sort guideline appraisal with agree ii systematic review of the current evidence on how users handle the 2 overall assessments
url http://europepmc.org/articles/PMC5373625?pdf=render
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