Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil
Carotid radiofrequency coils inside a PET/MRI system can result in PET quantification errors. We compared the performance of a dedicated PET/MRI carotid coil against a coil for MRI-only use. An <sup>18</sup>F-fluorodeoxyglucose (<sup>18</sup>F-FDG) phantom was scanned without...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-05-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/11/9/2569 |
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| author | Mueez Aizaz Jochem A. J. van der Pol Roel Wierts Hans Zwart Abe J. van der Werf Joachim E. Wildberger Jan A. Bucerius Rik P. M. Moonen Marianne Eline Kooi |
| author_facet | Mueez Aizaz Jochem A. J. van der Pol Roel Wierts Hans Zwart Abe J. van der Werf Joachim E. Wildberger Jan A. Bucerius Rik P. M. Moonen Marianne Eline Kooi |
| author_sort | Mueez Aizaz |
| collection | DOAJ |
| description | Carotid radiofrequency coils inside a PET/MRI system can result in PET quantification errors. We compared the performance of a dedicated PET/MRI carotid coil against a coil for MRI-only use. An <sup>18</sup>F-fluorodeoxyglucose (<sup>18</sup>F-FDG) phantom was scanned without and with an MRI-only coil and with the PET/MRI coil. The decay-corrected normalized activity was compared for the different coil configurations. Eighteen patients were scanned with the three coil configurations. The maximal standardized uptake values (SUV<sub>max</sub>) and signal-to-noise ratios (SNR) were calculated. Repeated measures ANOVA was performed to assess the differences in SUV<sub>max</sub> and SNR between the coil configurations. In the phantom study, the PET/MRI coil demonstrated a slight decrease (<5%), while the MRI-only coil showed a substantial decrease (up to 10%) in normalized activity at the position of coil elements compared to no dedicated coil configuration. In the patient study, the SUV<sub>max</sub> values for both no surface coil (3.59 ± 0.15) and PET/MRI coil (3.54 ± 0.15) were significantly higher (<i>p</i> = 0.03 and <i>p</i> = 0.04, respectively) as compared to the MRI-only coil (3.28 ± 0.16). No significant difference was observed between PET/MRI and no surface coil (<i>p</i> = 1.0). The SNR values for both PET/MRI (7.31 ± 0.44) and MRI-only (7.62 ± 0.42) configurations demonstrated significantly higher (<i>p</i> < 0.001) SNR values as compared to the no surface coil (3.78 ± 0.22), while no significant difference was observed in SNR between the PET/MRI and MRI-only coil (<i>p</i> = 1.0). This study demonstrated that the PET/MRI coil can be used for PET imaging without requiring attenuation correction while acquiring high-resolution MR images. |
| first_indexed | 2024-03-10T04:00:53Z |
| format | Article |
| id | doaj.art-db3cfc07398a4a5b90811c351d1608c5 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T04:00:53Z |
| publishDate | 2022-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-db3cfc07398a4a5b90811c351d1608c52023-11-23T08:34:12ZengMDPI AGJournal of Clinical Medicine2077-03832022-05-01119256910.3390/jcm11092569Evaluation of a Dedicated Radiofrequency Carotid PET/MRI CoilMueez Aizaz0Jochem A. J. van der Pol1Roel Wierts2Hans Zwart3Abe J. van der Werf4Joachim E. Wildberger5Jan A. Bucerius6Rik P. M. Moonen7Marianne Eline Kooi8Department of Radiology and Nuclear Medicine, Maastricht University Medical Center+, 6202 AZ Maastricht, The NetherlandsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, 6202 AZ Maastricht, The NetherlandsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, 6202 AZ Maastricht, The NetherlandsMachnet B.V, 9301 LK Roden, The NetherlandsMachnet B.V, 9301 LK Roden, The NetherlandsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, 6202 AZ Maastricht, The NetherlandsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, 6202 AZ Maastricht, The NetherlandsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, 6202 AZ Maastricht, The NetherlandsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Center+, 6202 AZ Maastricht, The NetherlandsCarotid radiofrequency coils inside a PET/MRI system can result in PET quantification errors. We compared the performance of a dedicated PET/MRI carotid coil against a coil for MRI-only use. An <sup>18</sup>F-fluorodeoxyglucose (<sup>18</sup>F-FDG) phantom was scanned without and with an MRI-only coil and with the PET/MRI coil. The decay-corrected normalized activity was compared for the different coil configurations. Eighteen patients were scanned with the three coil configurations. The maximal standardized uptake values (SUV<sub>max</sub>) and signal-to-noise ratios (SNR) were calculated. Repeated measures ANOVA was performed to assess the differences in SUV<sub>max</sub> and SNR between the coil configurations. In the phantom study, the PET/MRI coil demonstrated a slight decrease (<5%), while the MRI-only coil showed a substantial decrease (up to 10%) in normalized activity at the position of coil elements compared to no dedicated coil configuration. In the patient study, the SUV<sub>max</sub> values for both no surface coil (3.59 ± 0.15) and PET/MRI coil (3.54 ± 0.15) were significantly higher (<i>p</i> = 0.03 and <i>p</i> = 0.04, respectively) as compared to the MRI-only coil (3.28 ± 0.16). No significant difference was observed between PET/MRI and no surface coil (<i>p</i> = 1.0). The SNR values for both PET/MRI (7.31 ± 0.44) and MRI-only (7.62 ± 0.42) configurations demonstrated significantly higher (<i>p</i> < 0.001) SNR values as compared to the no surface coil (3.78 ± 0.22), while no significant difference was observed in SNR between the PET/MRI and MRI-only coil (<i>p</i> = 1.0). This study demonstrated that the PET/MRI coil can be used for PET imaging without requiring attenuation correction while acquiring high-resolution MR images.https://www.mdpi.com/2077-0383/11/9/2569carotid imagingflexible MRI coilsPET/MRIattenuation correction |
| spellingShingle | Mueez Aizaz Jochem A. J. van der Pol Roel Wierts Hans Zwart Abe J. van der Werf Joachim E. Wildberger Jan A. Bucerius Rik P. M. Moonen Marianne Eline Kooi Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil Journal of Clinical Medicine carotid imaging flexible MRI coils PET/MRI attenuation correction |
| title | Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil |
| title_full | Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil |
| title_fullStr | Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil |
| title_full_unstemmed | Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil |
| title_short | Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil |
| title_sort | evaluation of a dedicated radiofrequency carotid pet mri coil |
| topic | carotid imaging flexible MRI coils PET/MRI attenuation correction |
| url | https://www.mdpi.com/2077-0383/11/9/2569 |
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