Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal Disease

Pathogenic bacteria, originating in the inflamed periodontium, can make their way into the body through the vascular system, either by entering the bloodstream or lymph directly or as internalized particles of immune cells. This research aims to investigate the existence of a potential connection be...

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Main Authors: Ioana VOINESCU, Dumitru FERECHIDE
Format: Article
Language:English
Published: Media Med Publicis 2021-12-01
Series:Modern Medicine
Subjects:
Online Access:https://medicinamoderna.ro/wp-content/uploads/2021/12/Statistical-Study-Regarding-the-Presence-of-Gram-Bacteria-in-Patients-with-Cardiovascular-Disease-and-Periodontal-Disease-8.pdf
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author Ioana VOINESCU
Dumitru FERECHIDE
author_facet Ioana VOINESCU
Dumitru FERECHIDE
author_sort Ioana VOINESCU
collection DOAJ
description Pathogenic bacteria, originating in the inflamed periodontium, can make their way into the body through the vascular system, either by entering the bloodstream or lymph directly or as internalized particles of immune cells. This research aims to investigate the existence of a potential connection between two pathologies – periodontitis and ischemic heart disease – by utilizing a DNA-DNA hybridization technique to highlight the presence of seven periodontal pathogens: A. actinomycetemcomitans, P. gingivalis, P. endodontalis, P. intermedia, T. forsythia, C. rectus and F. Nucleatum. The study was conducted over a period of 3 years on a sample consisting of 119 patients with cardiovascular disease and periodontal disease, divided into 3 groups by pathologies, as follows: the first group consisted of 31 patients with ischemic cardiomyopathy, the second group consisted of 43 patients with periodontal disease and ischemic cardiomyopathy, and the third group consisted of 45 patients with periodontal disease. The results show the possibility of a correlation between the composition of the bacterial flora in the group of patients with cardiac disease and those with associated pathologies. In conclusion, we may state that periodontitis may be seen as a risk factor in heart disease, which may certify the possibility of an etiological connection between the two pathologies.
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spelling doaj.art-db3d0c8380b840559df556dea134a7f82022-12-21T17:49:18ZengMedia Med PublicisModern Medicine1223-04722360-24732021-12-01284413417https://doi.org/10.31689/rmm.2021.28.4.413Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal DiseaseIoana VOINESCU0Dumitru FERECHIDE1https://orcid.org/0000-0002-0357-8479„Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania„Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaPathogenic bacteria, originating in the inflamed periodontium, can make their way into the body through the vascular system, either by entering the bloodstream or lymph directly or as internalized particles of immune cells. This research aims to investigate the existence of a potential connection between two pathologies – periodontitis and ischemic heart disease – by utilizing a DNA-DNA hybridization technique to highlight the presence of seven periodontal pathogens: A. actinomycetemcomitans, P. gingivalis, P. endodontalis, P. intermedia, T. forsythia, C. rectus and F. Nucleatum. The study was conducted over a period of 3 years on a sample consisting of 119 patients with cardiovascular disease and periodontal disease, divided into 3 groups by pathologies, as follows: the first group consisted of 31 patients with ischemic cardiomyopathy, the second group consisted of 43 patients with periodontal disease and ischemic cardiomyopathy, and the third group consisted of 45 patients with periodontal disease. The results show the possibility of a correlation between the composition of the bacterial flora in the group of patients with cardiac disease and those with associated pathologies. In conclusion, we may state that periodontitis may be seen as a risk factor in heart disease, which may certify the possibility of an etiological connection between the two pathologies.https://medicinamoderna.ro/wp-content/uploads/2021/12/Statistical-Study-Regarding-the-Presence-of-Gram-Bacteria-in-Patients-with-Cardiovascular-Disease-and-Periodontal-Disease-8.pdfperiodontal diseaseischemic cardiomyopathygram-negative bacteria
spellingShingle Ioana VOINESCU
Dumitru FERECHIDE
Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal Disease
Modern Medicine
periodontal disease
ischemic cardiomyopathy
gram-negative bacteria
title Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal Disease
title_full Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal Disease
title_fullStr Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal Disease
title_full_unstemmed Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal Disease
title_short Statistical Study Regarding the Presence of Gram Bacteria in Patients with Cardiovascular Disease and Periodontal Disease
title_sort statistical study regarding the presence of gram bacteria in patients with cardiovascular disease and periodontal disease
topic periodontal disease
ischemic cardiomyopathy
gram-negative bacteria
url https://medicinamoderna.ro/wp-content/uploads/2021/12/Statistical-Study-Regarding-the-Presence-of-Gram-Bacteria-in-Patients-with-Cardiovascular-Disease-and-Periodontal-Disease-8.pdf
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AT dumitruferechide statisticalstudyregardingthepresenceofgrambacteriainpatientswithcardiovasculardiseaseandperiodontaldisease