THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITIS
Introduction. Infective endocarditis (IE) is a severe cardiovascular disorder involving native valves, ventricular or atrial endocardium, foreign intracardiac bodies (prosthetic valves, pacemaker or intracardiac defibrillator), and extracardiac (neurological, nephrological, musculoskeletal syst...
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| Format: | Article |
| Language: | English |
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Balkan Medical Union
2018-06-01
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| Series: | Archives of the Balkan Medical Union |
| Subjects: | |
| Online Access: | http://umbalk.org/wp-content/uploads/2018/06/03.The-musculoskeletal-system-involvement-in-patients.pdf |
| _version_ | 1828845975191420928 |
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| author | Alexandra GREJDIERU Elena SAMOHVALOV Lucia MAZUR-NICORICI Livi GRIB |
| author_facet | Alexandra GREJDIERU Elena SAMOHVALOV Lucia MAZUR-NICORICI Livi GRIB |
| author_sort | Alexandra GREJDIERU |
| collection | DOAJ |
| description | Introduction. Infective endocarditis (IE) is a severe
cardiovascular disorder involving native valves, ventricular
or atrial endocardium, foreign intracardiac
bodies (prosthetic valves, pacemaker or intracardiac
defibrillator), and extracardiac (neurological, nephrological,
musculoskeletal system etc.) complications with
high mortality and poor prognosis.
The objectives of the study were to evaluate clinical
and laboratory features of infective endocarditis with
musculoskeletal manifestations.
Methods. The study was conducted on a sample of
235 patients, 185 being hospitalized in specialized
Cardiology Departments, including four medical centers,
between November 2014 and March 2016. All
patients included in the study fulfilled the diagnostic
criteria for infective endocarditis developed after
Duke Endocarditis Service (Durham, North Carolina),
revised in 1994 and 2007.
Results. According to the presence or absence of
musculoskeletal manifestations (MSM), patients were
divided in 2 groups: 1st group – 90 patients with IE
and MSM (38%) and 2nd group – 145 patients with
IE without MSM (72%). In this way we found that
women develop musculoskeletal symptoms more frequently
than men – 44% vs. 36%, although MS symptoms were found in 38% of study patients. The highest incidence of IE in the general study group was seen in men – 70% vs. women – 30% respectively (p = 0.022). Conclusions. From all predisposing cardiac factors in IE patients with MSM the most prevalent ones were: rheumatic valvular heart disease (33%) and valvular prostheses (24%), the predominant bacteremia source being the respiratory infections (52%), poor dental hygiene (33%) and tonsillitis (24%) occurring in patients with diabetes mellitus (23%) and hepatitis (21%). |
| first_indexed | 2024-12-12T21:38:35Z |
| format | Article |
| id | doaj.art-db3dc01b74d34aafb7af153563c0ece9 |
| institution | Directory Open Access Journal |
| issn | 1584-9244 2558-815X |
| language | English |
| last_indexed | 2024-12-12T21:38:35Z |
| publishDate | 2018-06-01 |
| publisher | Balkan Medical Union |
| record_format | Article |
| series | Archives of the Balkan Medical Union |
| spelling | doaj.art-db3dc01b74d34aafb7af153563c0ece92022-12-22T00:11:07ZengBalkan Medical UnionArchives of the Balkan Medical Union1584-92442558-815X2018-06-01532196199https://doi.org/10.31688/ABMU.2018.53.2.03THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITISAlexandra GREJDIERU0Elena SAMOHVALOV1Lucia MAZUR-NICORICI2Livi GRIB3 Department of Internal Medicine, State University of Medicine and Pharmacy „Nicolae Testemitanu“, Chisinau, Republic of Moldova Department of Internal Medicine, State University of Medicine and Pharmacy „Nicolae Testemitanu“, Chisinau, Republic of Moldova Department of Internal Medicine, State University of Medicine and Pharmacy „Nicolae Testemitanu“, Chisinau, Republic of Moldova Department of Internal Medicine, State University of Medicine and Pharmacy „Nicolae Testemitanu“, Chisinau, Republic of MoldovaIntroduction. Infective endocarditis (IE) is a severe cardiovascular disorder involving native valves, ventricular or atrial endocardium, foreign intracardiac bodies (prosthetic valves, pacemaker or intracardiac defibrillator), and extracardiac (neurological, nephrological, musculoskeletal system etc.) complications with high mortality and poor prognosis. The objectives of the study were to evaluate clinical and laboratory features of infective endocarditis with musculoskeletal manifestations. Methods. The study was conducted on a sample of 235 patients, 185 being hospitalized in specialized Cardiology Departments, including four medical centers, between November 2014 and March 2016. All patients included in the study fulfilled the diagnostic criteria for infective endocarditis developed after Duke Endocarditis Service (Durham, North Carolina), revised in 1994 and 2007. Results. According to the presence or absence of musculoskeletal manifestations (MSM), patients were divided in 2 groups: 1st group – 90 patients with IE and MSM (38%) and 2nd group – 145 patients with IE without MSM (72%). In this way we found that women develop musculoskeletal symptoms more frequently than men – 44% vs. 36%, although MS symptoms were found in 38% of study patients. The highest incidence of IE in the general study group was seen in men – 70% vs. women – 30% respectively (p = 0.022). Conclusions. From all predisposing cardiac factors in IE patients with MSM the most prevalent ones were: rheumatic valvular heart disease (33%) and valvular prostheses (24%), the predominant bacteremia source being the respiratory infections (52%), poor dental hygiene (33%) and tonsillitis (24%) occurring in patients with diabetes mellitus (23%) and hepatitis (21%).http://umbalk.org/wp-content/uploads/2018/06/03.The-musculoskeletal-system-involvement-in-patients.pdfinfective endocarditismusculoskeletal manifestationscomplications |
| spellingShingle | Alexandra GREJDIERU Elena SAMOHVALOV Lucia MAZUR-NICORICI Livi GRIB THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITIS Archives of the Balkan Medical Union infective endocarditis musculoskeletal manifestations complications |
| title | THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITIS |
| title_full | THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITIS |
| title_fullStr | THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITIS |
| title_full_unstemmed | THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITIS |
| title_short | THE MUSCULOSKELETAL SYSTEM INVOLVEMENT IN PATIENTS WITH INFECTIVE ENDOCARDITIS |
| title_sort | musculoskeletal system involvement in patients with infective endocarditis |
| topic | infective endocarditis musculoskeletal manifestations complications |
| url | http://umbalk.org/wp-content/uploads/2018/06/03.The-musculoskeletal-system-involvement-in-patients.pdf |
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