Inflammasome Activation in Myeloid Malignancies—Friend or Foe?

Inflammasome Activation in Myeloid Malignancies—Friend or Foe?

Myeloid malignancies including myelodysplastic syndromes, myeloproliferative neoplasms and acute myeloid leukemia are heterogeneous disorders originating from mutated hematopoietic stem and progenitor cells (HSPCs). Genetically, they are very heterogeneous and characterized by uncontrolled prolifera...

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Bibliographic Details
Main Authors: Nicola Andina, Nicolas Bonadies, Ramanjaneyulu Allam
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-01-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
NLRP3 inflammasome
myeloid malignancies
myelodysplastic syndromes
myeloproliferative neoplasms
chronic myeloid leukemia
acute myeloid leukemia and targeting inflammasomes
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.825611/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.825611/full

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