Initial exploration of a novel fusion protein, IL-4/IL-34/IL-10, which promotes cardiac allograft survival mice through alloregulation

Immune mediated graft loss still represents a major risk to transplant recipients. Creative approaches to immunosuppression that exploit the recipient's own alloregulatory mechanisms could reduce the need for pharmacologic immunosuppression and potentially induce immune tolerance. In the proces...

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Bibliographic Details
Main Authors: Young S. Lee, I-Ting Cheng, Godoy-Ruiz Raquel, David J. Weber, Joseph R. Scalea
Format: Article
Language:English
Published: SAGE Publishing 2023-10-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/17534259231186239