Nucleoporin mediated nuclear positioning and silencing of HMR.

The organization of chromatin domains in the nucleus is an important factor in gene regulation. In eukaryotic nuclei, transcriptionally silenced chromatin clusters at the nuclear periphery while transcriptionally poised chromatin resides in the nuclear interior. Recent studies suggest that nuclear p...

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Bibliographic Details
Main Authors: Giulia J Ruben, Jacob G Kirkland, Tracy MacDonough, Miao Chen, Rudra N Dubey, Marc R Gartenberg, Rohinton T Kamakaka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3139579?pdf=render