Cytotoxicity evaluation of methacrylate- and silorane-based composite resins

Objectives: The objective of this study was to investigate and compare the cytotoxic effects of four composite resin materials with different content. Material and Methods: Two traditional methacrylate-based (Clearfil AP-X, RefleXions), as well as a self-adhering methacrylate-based (Vertise Flow) an...

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Main Authors: Digdem Eren, Gulsah Goktolga Akin, Ozden Ozel Bektas, Zubeyde Akin Polat
Format: Article
Language:English
Published: Cumhuriyet University 2012-08-01
Series:Cumhuriyet Dental Journal
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/48366
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author Digdem Eren
Gulsah Goktolga Akin
Ozden Ozel Bektas
Zubeyde Akin Polat
author_facet Digdem Eren
Gulsah Goktolga Akin
Ozden Ozel Bektas
Zubeyde Akin Polat
author_sort Digdem Eren
collection DOAJ
description Objectives: The objective of this study was to investigate and compare the cytotoxic effects of four composite resin materials with different content. Material and Methods: Two traditional methacrylate-based (Clearfil AP-X, RefleXions), as well as a self-adhering methacrylate-based (Vertise Flow) and a silorane-based (Filtek Silorane) composite resin were tested in the experiment. Ten cylindrical specimens were made of each material, using a mould (2mm. thick and 8 mm. in diameter). An agar diffusion method was employed, and cytotoxicity rankings were determined using lysis index scores. For statistical analysis, Kruskal-Wallis and Mann-Whitney U-tests were used. Results: Amongst the composite resins, the silorane-based composite was found to be less cytotoxic than the methacrylate-based composite resins, which all had the same cytotoxicity ranking. Conclusions: The silorane-based composite resin was considered more biocompatible than the methacrylate-based composite resins.
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spelling doaj.art-db46b4c7bc5d4e70ae76cc774ec777cb2023-08-02T06:59:07ZengCumhuriyet UniversityCumhuriyet Dental Journal1302-58052146-28522012-08-0115432733410.7126/cdj.2012.16992057Cytotoxicity evaluation of methacrylate- and silorane-based composite resinsDigdem ErenGulsah Goktolga AkinOzden Ozel BektasZubeyde Akin PolatObjectives: The objective of this study was to investigate and compare the cytotoxic effects of four composite resin materials with different content. Material and Methods: Two traditional methacrylate-based (Clearfil AP-X, RefleXions), as well as a self-adhering methacrylate-based (Vertise Flow) and a silorane-based (Filtek Silorane) composite resin were tested in the experiment. Ten cylindrical specimens were made of each material, using a mould (2mm. thick and 8 mm. in diameter). An agar diffusion method was employed, and cytotoxicity rankings were determined using lysis index scores. For statistical analysis, Kruskal-Wallis and Mann-Whitney U-tests were used. Results: Amongst the composite resins, the silorane-based composite was found to be less cytotoxic than the methacrylate-based composite resins, which all had the same cytotoxicity ranking. Conclusions: The silorane-based composite resin was considered more biocompatible than the methacrylate-based composite resins.https://dergipark.org.tr/tr/download/article-file/48366cytotoxicity methacrylate-based composite resin silorane-based composite resin self-adhesive composite resin
spellingShingle Digdem Eren
Gulsah Goktolga Akin
Ozden Ozel Bektas
Zubeyde Akin Polat
Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
Cumhuriyet Dental Journal
cytotoxicity
methacrylate-based composite resin
silorane-based composite resin
self-adhesive composite resin
title Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
title_full Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
title_fullStr Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
title_full_unstemmed Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
title_short Cytotoxicity evaluation of methacrylate- and silorane-based composite resins
title_sort cytotoxicity evaluation of methacrylate and silorane based composite resins
topic cytotoxicity
methacrylate-based composite resin
silorane-based composite resin
self-adhesive composite resin
url https://dergipark.org.tr/tr/download/article-file/48366
work_keys_str_mv AT digdemeren cytotoxicityevaluationofmethacrylateandsiloranebasedcompositeresins
AT gulsahgoktolgaakin cytotoxicityevaluationofmethacrylateandsiloranebasedcompositeresins
AT ozdenozelbektas cytotoxicityevaluationofmethacrylateandsiloranebasedcompositeresins
AT zubeydeakinpolat cytotoxicityevaluationofmethacrylateandsiloranebasedcompositeresins