The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities
The prenatal period and the first years of life have a significant impact on the health issues and life quality of an individual. The appropriate development of the immune system and the central nervous system are thought to be major critical determining events. In parallel to these, establishing an...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Life |
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| Online Access: | https://www.mdpi.com/2075-1729/12/3/424 |
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| author | Eva Miko Andras Csaszar Jozsef Bodis Kalman Kovacs |
| author_facet | Eva Miko Andras Csaszar Jozsef Bodis Kalman Kovacs |
| author_sort | Eva Miko |
| collection | DOAJ |
| description | The prenatal period and the first years of life have a significant impact on the health issues and life quality of an individual. The appropriate development of the immune system and the central nervous system are thought to be major critical determining events. In parallel to these, establishing an early intestinal microbiota community is another important factor for future well-being interfering with prenatal and postnatal developmental processes. This review aims at summarizing the main characteristics of maternal gut microbiota and its possible transmission to the offspring, thereby affecting fetal and/or neonatal development and health. Since maternal dietary factors are potential modulators of the maternal–fetal microbiota axis, we will outline current knowledge on the impact of certain diets, nutritional factors, and nutritional modulators during pregnancy on offspring’s microbiota and health. |
| first_indexed | 2024-03-09T13:34:35Z |
| format | Article |
| id | doaj.art-db477ad7c74c44d4b92f8777f5f118ae |
| institution | Directory Open Access Journal |
| issn | 2075-1729 |
| language | English |
| last_indexed | 2024-03-09T13:34:35Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Life |
| spelling | doaj.art-db477ad7c74c44d4b92f8777f5f118ae2023-11-30T21:14:31ZengMDPI AGLife2075-17292022-03-0112342410.3390/life12030424The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation PossibilitiesEva Miko0Andras Csaszar1Jozsef Bodis2Kalman Kovacs3Department of Medical Microbiology and Immunology, Medical School, University of Pécs, 12 Szigeti Street, 7624 Pécs, HungaryNational Laboratory for Human Reproduction, University of Pécs, 7624 Pécs, HungaryNational Laboratory for Human Reproduction, University of Pécs, 7624 Pécs, HungaryNational Laboratory for Human Reproduction, University of Pécs, 7624 Pécs, HungaryThe prenatal period and the first years of life have a significant impact on the health issues and life quality of an individual. The appropriate development of the immune system and the central nervous system are thought to be major critical determining events. In parallel to these, establishing an early intestinal microbiota community is another important factor for future well-being interfering with prenatal and postnatal developmental processes. This review aims at summarizing the main characteristics of maternal gut microbiota and its possible transmission to the offspring, thereby affecting fetal and/or neonatal development and health. Since maternal dietary factors are potential modulators of the maternal–fetal microbiota axis, we will outline current knowledge on the impact of certain diets, nutritional factors, and nutritional modulators during pregnancy on offspring’s microbiota and health.https://www.mdpi.com/2075-1729/12/3/424gut microbiotapregnancyfetal developmentmaternal nutritionprobiotics |
| spellingShingle | Eva Miko Andras Csaszar Jozsef Bodis Kalman Kovacs The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities Life gut microbiota pregnancy fetal development maternal nutrition probiotics |
| title | The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities |
| title_full | The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities |
| title_fullStr | The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities |
| title_full_unstemmed | The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities |
| title_short | The Maternal–Fetal Gut Microbiota Axis: Physiological Changes, Dietary Influence, and Modulation Possibilities |
| title_sort | maternal fetal gut microbiota axis physiological changes dietary influence and modulation possibilities |
| topic | gut microbiota pregnancy fetal development maternal nutrition probiotics |
| url | https://www.mdpi.com/2075-1729/12/3/424 |
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