PPLook: an automated data mining tool for protein-protein interaction
<p>Abstract</p> <p>Background</p> <p>Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of interactions among proteins. There is a lack of tools to extract PPI, v...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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BMC
2010-06-01
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| Series: | BMC Bioinformatics |
| Online Access: | http://www.biomedcentral.com/1471-2105/11/326 |
| _version_ | 1818272669372514304 |
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| author | Xia Li Li Yao-Jun Zhang Shao-Wu Pan Quan |
| author_facet | Xia Li Li Yao-Jun Zhang Shao-Wu Pan Quan |
| author_sort | Xia Li |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of interactions among proteins. There is a lack of tools to extract PPI, visualize and classify the results.</p> <p>Results</p> <p>We developed a PPI search system, termed PPLook, which automatically extracts and visualizes protein-protein interaction (PPI) from text. Given a query protein name, PPLook can search a dataset for other proteins interacting with it by using a keywords dictionary pattern-matching algorithm, and display the topological parameters, such as the number of nodes, edges, and connected components. The visualization component of PPLook enables us to view the interaction relationship among the proteins in a three-dimensional space based on the OpenGL graphics interface technology. PPLook can also provide the functions of selecting protein semantic class, counting the number of semantic class proteins which interact with query protein, counting the literature number of articles appearing the interaction relationship about the query protein. Moreover, PPLook provides heterogeneous search and a user-friendly graphical interface.</p> <p>Conclusions</p> <p>PPLook is an effective tool for biologists and biosystem developers who need to access PPI information from the literature. PPLook is freely available for non-commercial users at <url>http://meta.usc.edu/softs/PPLook</url>.</p> |
| first_indexed | 2024-12-12T21:45:44Z |
| format | Article |
| id | doaj.art-db4e6dc2a3a640f58920b456394595b5 |
| institution | Directory Open Access Journal |
| issn | 1471-2105 |
| language | English |
| last_indexed | 2024-12-12T21:45:44Z |
| publishDate | 2010-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Bioinformatics |
| spelling | doaj.art-db4e6dc2a3a640f58920b456394595b52022-12-22T00:10:55ZengBMCBMC Bioinformatics1471-21052010-06-0111132610.1186/1471-2105-11-326PPLook: an automated data mining tool for protein-protein interactionXia LiLi Yao-JunZhang Shao-WuPan Quan<p>Abstract</p> <p>Background</p> <p>Extracting and visualizing of protein-protein interaction (PPI) from text literatures are a meaningful topic in protein science. It assists the identification of interactions among proteins. There is a lack of tools to extract PPI, visualize and classify the results.</p> <p>Results</p> <p>We developed a PPI search system, termed PPLook, which automatically extracts and visualizes protein-protein interaction (PPI) from text. Given a query protein name, PPLook can search a dataset for other proteins interacting with it by using a keywords dictionary pattern-matching algorithm, and display the topological parameters, such as the number of nodes, edges, and connected components. The visualization component of PPLook enables us to view the interaction relationship among the proteins in a three-dimensional space based on the OpenGL graphics interface technology. PPLook can also provide the functions of selecting protein semantic class, counting the number of semantic class proteins which interact with query protein, counting the literature number of articles appearing the interaction relationship about the query protein. Moreover, PPLook provides heterogeneous search and a user-friendly graphical interface.</p> <p>Conclusions</p> <p>PPLook is an effective tool for biologists and biosystem developers who need to access PPI information from the literature. PPLook is freely available for non-commercial users at <url>http://meta.usc.edu/softs/PPLook</url>.</p>http://www.biomedcentral.com/1471-2105/11/326 |
| spellingShingle | Xia Li Li Yao-Jun Zhang Shao-Wu Pan Quan PPLook: an automated data mining tool for protein-protein interaction BMC Bioinformatics |
| title | PPLook: an automated data mining tool for protein-protein interaction |
| title_full | PPLook: an automated data mining tool for protein-protein interaction |
| title_fullStr | PPLook: an automated data mining tool for protein-protein interaction |
| title_full_unstemmed | PPLook: an automated data mining tool for protein-protein interaction |
| title_short | PPLook: an automated data mining tool for protein-protein interaction |
| title_sort | pplook an automated data mining tool for protein protein interaction |
| url | http://www.biomedcentral.com/1471-2105/11/326 |
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