Regulatory logic of endogenous RNAi in silencing de novo genomic conflicts.

Although the biological utilities of endogenous RNAi (endo-RNAi) have been largely elusive, recent studies reveal its critical role in the non-model fruitfly Drosophila simulans to suppress selfish genes, whose unchecked activities can severely impair spermatogenesis. In particular, hairpin RNA (hpR...

全面介紹

書目詳細資料
Main Authors: Jeffrey Vedanayagam, Ching-Jung Lin, Ranjith Papareddy, Michael Nodine, Alex S Flynt, Jiayu Wen, Eric C Lai
格式: Article
語言:English
出版: Public Library of Science (PLoS) 2023-06-01
叢編:PLoS Genetics
在線閱讀:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010787&type=printable