Chordoid Meningioma with Extensive Lymphocytic Infiltration Forming Lymphoid Follicles: A Case Report
Background: Meningiomas, the most common primary central nervous system (CNS) tumors, include 15 distinct subtypes reflecting its broad morphological spectrum. Most subtypes have a benign clinical course and correspond to CNS World Health Organization (WHO) grade I. Chordoid meningiomas are a rare s...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Kasr Al-Ainy Center of Clinical Oncology and Nuclear Medicine
2023-12-01
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| Series: | Research in Oncology |
| Subjects: | |
| Online Access: | https://resoncol.journals.ekb.eg/article_317780_0c1f18f11dfaa7cd5dad11e631e77421.pdf |
| Summary: | Background: Meningiomas, the most common primary central nervous system (CNS) tumors, include 15 distinct subtypes reflecting its broad morphological spectrum. Most subtypes have a benign clinical course and correspond to CNS World Health Organization (WHO) grade I. Chordoid meningiomas are a rare subtype (0.5% of all meningiomas) with relatively aggressive behavior and are classified as WHO grade II. Case presentation: We present a case of a 20-year-old man who presented to the emergency room with convulsions. A right parietal cerebral mass with peritumoral edema and a significant mass effect was discovered by magnetic resonance imaging. There was no systemic manifestations and hematological tests were normal. He underwent surgery and a histopathological examination of the excised tumor revealed the diagnosis of chordoid meningioma, WHO grade II. In addition, there was dense lymphocytic infiltration forming lymphoid follicles. Conclusion: Chordoid meningioma may be associated with extensive lymphoid infiltration with follicle formation in the absence of systemic or hematologic manifestations. |
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| ISSN: | 2357-0687 2357-0695 |