Structural plasticity of the axon initial segment in rat hippocampal granule cells following high frequency stimulation and LTP induction

The axon initial segment (AIS) is the site of action potential initiation and important for the integration of synaptic input. Length and localization of the AIS are dynamic, modulated by afferent activity and contribute to the homeostatic control of neuronal excitability. Synaptopodin is a plastici...

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Bibliographic Details
Main Authors: Tassilo Jungenitz, Alexander Bird, Maren Engelhardt, Peter Jedlicka, Stephan W. Schwarzacher, Thomas Deller
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Neuroanatomy
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2023.1125623/full