Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection

Bronchorrhea is a watery sputum volume of at least 100 mL/day, which is commonly associated with lung malignancies. We report a 57-year-old woman was admitted to the hospital with a cough, profuse sputum. Chest CTs showed crazy paving pattern and lung nodules. Cell nests were visible on the Thinprep...

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Main Authors: Xin Liu, Xinyue Zhou, Xiaocong Zhang, Lingling Sun, Guangdan Zhao, Shitao Mao, Fangzhi Li, Xiu Gu, Paul J. Wolters, Shuo Liu
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Respiratory Medicine Case Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213007124000054
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author Xin Liu
Xinyue Zhou
Xiaocong Zhang
Lingling Sun
Guangdan Zhao
Shitao Mao
Fangzhi Li
Xiu Gu
Paul J. Wolters
Shuo Liu
author_facet Xin Liu
Xinyue Zhou
Xiaocong Zhang
Lingling Sun
Guangdan Zhao
Shitao Mao
Fangzhi Li
Xiu Gu
Paul J. Wolters
Shuo Liu
author_sort Xin Liu
collection DOAJ
description Bronchorrhea is a watery sputum volume of at least 100 mL/day, which is commonly associated with lung malignancies. We report a 57-year-old woman was admitted to the hospital with a cough, profuse sputum. Chest CTs showed crazy paving pattern and lung nodules. Cell nests were visible on the Thinprep Cytologic Test. The case was considered an invasive mucinous adenocarcinoma of the lung combined with bronchorrhea. Significantly, the sputum volume declined rapidly and did not rise again when the patient was diagnosed with COVID-19 and treated with nirmatrelvir/ritonavir. This case is suggestive of studies related to regulatory mediators associated with bronchorrhea.
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spelling doaj.art-db52d73226c042959460a629ed4a86312024-02-09T04:48:14ZengElsevierRespiratory Medicine Case Reports2213-00712024-01-0147101982Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infectionXin Liu0Xinyue Zhou1Xiaocong Zhang2Lingling Sun3Guangdan Zhao4Shitao Mao5Fangzhi Li6Xiu Gu7Paul J. Wolters8Shuo Liu9Department of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR ChinaDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine, Department of Medicine, University of California, San Francisco, CA, USADepartment of Respiratory Medicine, The Fourth Hospital of China Medical University, Shenyang, Liaoning, 110032, PR China; Corresponding author.Bronchorrhea is a watery sputum volume of at least 100 mL/day, which is commonly associated with lung malignancies. We report a 57-year-old woman was admitted to the hospital with a cough, profuse sputum. Chest CTs showed crazy paving pattern and lung nodules. Cell nests were visible on the Thinprep Cytologic Test. The case was considered an invasive mucinous adenocarcinoma of the lung combined with bronchorrhea. Significantly, the sputum volume declined rapidly and did not rise again when the patient was diagnosed with COVID-19 and treated with nirmatrelvir/ritonavir. This case is suggestive of studies related to regulatory mediators associated with bronchorrhea.http://www.sciencedirect.com/science/article/pii/S2213007124000054BronchorrheaInvasive mucinous adenocarcinomaCOVID-19
spellingShingle Xin Liu
Xinyue Zhou
Xiaocong Zhang
Lingling Sun
Guangdan Zhao
Shitao Mao
Fangzhi Li
Xiu Gu
Paul J. Wolters
Shuo Liu
Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection
Respiratory Medicine Case Reports
Bronchorrhea
Invasive mucinous adenocarcinoma
COVID-19
title Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection
title_full Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection
title_fullStr Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection
title_full_unstemmed Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection
title_short Invasive mucinous adenocarcinoma of the lung with bronchorrhea — A marked reduction volume of sputum after SARS-CoV-2 infection
title_sort invasive mucinous adenocarcinoma of the lung with bronchorrhea a marked reduction volume of sputum after sars cov 2 infection
topic Bronchorrhea
Invasive mucinous adenocarcinoma
COVID-19
url http://www.sciencedirect.com/science/article/pii/S2213007124000054
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