A multiplexed DNA FISH strategy for assessing genome architecture in Caenorhabditis elegans

A multiplexed DNA FISH strategy for assessing genome architecture in Caenorhabditis elegans

Eukaryotic DNA is highly organized within nuclei and this organization is important for genome function. Fluorescent in situ hybridization (FISH) approaches allow 3D architectures of genomes to be visualized. Scalable FISH technologies, which can be applied to whole animals, are needed to help unrav...

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Bibliographic Details
Main Authors: Brandon D Fields, Son C Nguyen, Guy Nir, Scott Kennedy
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2019-05-01
Series:eLife
Subjects:
DNA FISH
genome architecture
Oligopaint
Online Access:https://elifesciences.org/articles/42823

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