Heavy ion radiation exposure triggered higher intestinal tumor frequency and greater β-catenin activation than γ radiation in APC(Min/+) mice.
Risk of colorectal cancer (CRC) after exposure to low linear energy transfer (low-LET) radiation such as γ-ray is highlighted by the studies in atom bomb survivors. On the contrary, CRC risk prediction after exposure to high-LET cosmic heavy ion radiation exposure is hindered due to scarcity of in v...
Главные авторы: | Kamal Datta, Shubhankar Suman, Bhaskar V S Kallakury, Albert J Fornace |
---|---|
Формат: | Статья |
Язык: | English |
Опубликовано: |
Public Library of Science (PLoS)
2013-01-01
|
Серии: | PLoS ONE |
Online-ссылка: | http://europepmc.org/articles/PMC3605451?pdf=render |
Схожие документы
-
Exposure to heavy ion radiation induces persistent oxidative stress in mouse intestine.
по: Kamal Datta, и др.
Опубликовано: (2012-01-01) -
Heavy-ion radiation-induced colitis and colorectal carcinogenesis in Il10-/- mice display co-activation of β-catenin and NF-κB signaling.
по: Shubhankar Suman, и др.
Опубликовано: (2022-01-01) -
Long-term differential changes in mouse intestinal metabolomics after γ and heavy ion radiation exposure.
по: Amrita K Cheema, и др.
Опубликовано: (2014-01-01) -
Administration of ON 01210.Na after exposure to ionizing radiation protects bone marrow cells by attenuating DNA damage response
по: Suman Shubhankar, и др.
Опубликовано: (2012-01-01) -
High-LET-Radiation-Induced Persistent DNA Damage Response Signaling and Gastrointestinal Cancer Development
по: Kamendra Kumar, и др.
Опубликовано: (2023-06-01)