Central Composite Design (CCD) for the Optimisation of Ethosomal Gel Formulation of <i>Punica granatum</i> Extract: In Vitro and In Vivo Evaluations

Central Composite Design (CCD) for the Optimisation of Ethosomal Gel Formulation of <i>Punica granatum</i> Extract: In Vitro and In Vivo Evaluations

This research manuscript’s objective was to develop the <i>Punica granatum</i> extract ethosome gel. The use of nanotechnology can improve transdermal drug delivery permeation of its major bioactive compound β-sitosterol. The optimised and developed formulations were further studied in v...

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Bibliographic Details
Main Authors: Prawez Alam, Faiyaz Shakeel, Ahmed I. Foudah, Sultan Alshehri, Roshan Salfi, Mohammed H. Alqarni, Tariq M. Aljarba
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Gels
Subjects:
<i>Punica granatum</i> extracts
central composite design
ethosome gel
anti-inflammatory action
Online Access:https://www.mdpi.com/2310-2861/8/8/511

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https://www.mdpi.com/2310-2861/8/8/511

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