PTPRC promoted CD8+ T cell mediated tumor immunity and drug sensitivity in breast cancer: based on pan-cancer analysis and artificial intelligence modeling of immunogenic cell death-based drug sensitivity stratification

PTPRC promoted CD8+ T cell mediated tumor immunity and drug sensitivity in breast cancer: based on pan-cancer analysis and artificial intelligence modeling of immunogenic cell death-based drug sensitivity stratification

BackgroundImmunogenic cell death (ICD) is a result of immune cell infiltration (ICI)-mediated cell death, which is also a novel acknowledgment to regulate cellular stressor-mediated cell death, including drug therapy and radiotherapy.MethodsIn this study, TCGA and GEO data cohorts were put into arti...

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Bibliographic Details
Main Authors: Pengping Li, Wei Wang, Shaowen Wang, Guodong Cao, Tonghe Pan, Yuqing Huang, Hong Wan, Weijun Zhang, Yate Huang, Haigang Jin, Zhenyu Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Immunology
Subjects:
immunogenic cell death (ICD)
drug sensitivity
breast cancer
PTPRC
CD8+ T cell
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1145481/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1145481/full

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