Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain

Deficiency of MGAT2 increases energy expenditure without high-fat feeding and protects genetically obese mice from excessive weight gain

Acyl CoA:monoacylglycerol acyltransferase 2 (MGAT2) is thought to be crucial for dietary fat absorption. Indeed, mice lacking the enzyme (Mogat2−/−) are resistant to obesity and other metabolic disorders induced by high-fat feeding. However, these mice absorb normal quantities of fat. To explore whe...

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Bibliografiske detaljer
Main Authors: David W. Nelson, Yu Gao, Nicole M. Spencer, Taylor Banh, Chi-Liang Eric Yen
Format: Article
Sprog:English
Udgivet: Elsevier 2011-09-01
Serier:Journal of Lipid Research
Fag:
triacylglycerol
dietary fat
neutral lipid metabolism
monoacylglycerol acyltransferase
high fat
Online adgang:http://www.sciencedirect.com/science/article/pii/S0022227520408636

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http://www.sciencedirect.com/science/article/pii/S0022227520408636

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