High-Conductance Channel Formation in Yeast Mitochondria is Mediated by F-ATP Synthase e and g Subunits

High-Conductance Channel Formation in Yeast Mitochondria is Mediated by F-ATP Synthase e and g Subunits

Background/Aims: The permeability transition pore (PTP) is an unselective, Ca2+-dependent high conductance channel of the inner mitochondrial membrane whose molecular identity has long remained a mystery. The most recent hypothesis is that pore formation involves the F-ATP synthase, which consistent...

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Bibliographic Details
Main Authors: Michela Carraro, Vanessa Checchetto, Geppo Sartori, Roza Kucharczyk, Jean-Paul di Rago, Giovanni Minervini, Cinzia Franchin, Giorgio Arrigoni, Valentina Giorgio, Valeria Petronilli, Silvio C.E. Tosatto, Giovanna Lippe, Ildikó Szabó, Paolo Bernardi
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Yeast mitochondria
Mitochondrial megachannel
Permeability transition
F-ATP synthase
Calcium
Online Access:https://www.karger.com/Article/FullText/494864

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