Preparation and in vitro Release Mechanisms of Modified Pectin Matrix Tablets for Colon-Targeted Drug Delivery

Preparation and in vitro Release Mechanisms of Modified Pectin Matrix Tablets for Colon-Targeted Drug Delivery

To deliver bioactive components to the colon, an oral, colon-targeted, microparticle delivery system was developed based on pectin. Pectin was modified by mechanical activation, resulting in controllable release properties, as well as dramatic decreases in solubility. Mechanically activated pectins...

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Bibliographic Details
Main Authors: Chen Li, Jian-Bin Li, Cai-Yu Lei, Pei-Hua Liu
Format: Article
Language:English
Published: North Carolina State University 2017-01-01
Series:BioResources
Subjects:
Pectin; Matrix tablet; Colon; Mechanical activation; Releasing property
Online Access:http://ojs.cnr.ncsu.edu/index.php/BioRes/article/view/BioRes_12_1_1491_Li_In_vitro_Release_Mechanism_Modified_Pectin_Drug_Delivery

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