The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential Study
The adverse effects of depression on patients’ life have been reported but information about its effects on the sequential organization of the information processing stages remains poorly understood as previous studies focused only on distinct stages. This study adds to existing knowledge by examini...
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MDPI AG
2020-12-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/10/12/935 |
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| author | Daniel Kwasi Ahorsu Ken Chung Ho Hon Wong Michael Gar Chung Yiu Yat Fung Mok Ka Shun Lei Hector Wing Hong Tsang |
| author_facet | Daniel Kwasi Ahorsu Ken Chung Ho Hon Wong Michael Gar Chung Yiu Yat Fung Mok Ka Shun Lei Hector Wing Hong Tsang |
| author_sort | Daniel Kwasi Ahorsu |
| collection | DOAJ |
| description | The adverse effects of depression on patients’ life have been reported but information about its effects on the sequential organization of the information processing stages remains poorly understood as previous studies focused only on distinct stages. This study adds to existing knowledge by examining the effect of major depressive disorder (MDD) on the sequential organization of information processing, executive and community functioning. Fifty-seven participants with 19 participants each for first episode depression (FMDD), recurrent episodes depression (RMDD), and healthy controls (HCs) participated in this study. They completed assessments on executive and community functioning measures, and choice reaction time task (CRTT) for the event-related potential (ERP) data. Findings revealed no significant between-group difference in executive functioning but participants with depression (FMDD and RMDD) were found to be more depressed, with FMDD participants having worse community functioning skills compared with HCs. There was no significant between-group main effect on behavioral data. ERP data showed significantly less positive-going P3b among RMDD participants compared with HCs. FMDD participants used a different information processing strategy at P1, while HCs and RMDD participants used a different processing strategy at N2b compared with the other group(s), respectively. The results suggest the use of multifaceted assessment to get a holistic view of the health status of people with MDD in order to inform clinicians on the appropriate interventional strategies needed for the patient. |
| first_indexed | 2024-03-10T14:19:51Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T14:19:51Z |
| publishDate | 2020-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-db627de3d71f48bf9e99505de9a3c1b22023-11-20T23:30:02ZengMDPI AGBrain Sciences2076-34252020-12-01101293510.3390/brainsci10120935The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential StudyDaniel Kwasi Ahorsu0Ken Chung1Ho Hon Wong2Michael Gar Chung Yiu3Yat Fung Mok4Ka Shun Lei5Hector Wing Hong Tsang6Neuropsychiatric Rehabilitation Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, ChinaNeuropsychiatric Rehabilitation Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, ChinaYung Fung Shee Psychiatric Center, Department of Psychiatry of United Christian Hospital, The Hong Kong Hospital Authority, Hong Kong SAR, ChinaYung Fung Shee Psychiatric Center, Department of Psychiatry of United Christian Hospital, The Hong Kong Hospital Authority, Hong Kong SAR, ChinaNeuropsychiatric Rehabilitation Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, ChinaNeuropsychiatric Rehabilitation Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, ChinaNeuropsychiatric Rehabilitation Laboratory, Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, ChinaThe adverse effects of depression on patients’ life have been reported but information about its effects on the sequential organization of the information processing stages remains poorly understood as previous studies focused only on distinct stages. This study adds to existing knowledge by examining the effect of major depressive disorder (MDD) on the sequential organization of information processing, executive and community functioning. Fifty-seven participants with 19 participants each for first episode depression (FMDD), recurrent episodes depression (RMDD), and healthy controls (HCs) participated in this study. They completed assessments on executive and community functioning measures, and choice reaction time task (CRTT) for the event-related potential (ERP) data. Findings revealed no significant between-group difference in executive functioning but participants with depression (FMDD and RMDD) were found to be more depressed, with FMDD participants having worse community functioning skills compared with HCs. There was no significant between-group main effect on behavioral data. ERP data showed significantly less positive-going P3b among RMDD participants compared with HCs. FMDD participants used a different information processing strategy at P1, while HCs and RMDD participants used a different processing strategy at N2b compared with the other group(s), respectively. The results suggest the use of multifaceted assessment to get a holistic view of the health status of people with MDD in order to inform clinicians on the appropriate interventional strategies needed for the patient.https://www.mdpi.com/2076-3425/10/12/935major depressive disorderinformation processingexecutive functioncommunity functionevent-related potentialchoice reaction time task |
| spellingShingle | Daniel Kwasi Ahorsu Ken Chung Ho Hon Wong Michael Gar Chung Yiu Yat Fung Mok Ka Shun Lei Hector Wing Hong Tsang The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential Study Brain Sciences major depressive disorder information processing executive function community function event-related potential choice reaction time task |
| title | The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential Study |
| title_full | The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential Study |
| title_fullStr | The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential Study |
| title_full_unstemmed | The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential Study |
| title_short | The Effects of Major Depressive Disorder on the Sequential Organization of Information Processing Stages: An Event-Related Potential Study |
| title_sort | effects of major depressive disorder on the sequential organization of information processing stages an event related potential study |
| topic | major depressive disorder information processing executive function community function event-related potential choice reaction time task |
| url | https://www.mdpi.com/2076-3425/10/12/935 |
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