Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic Review
Objective: The objective of this meta-analysis was to evaluate the effectiveness of endovascular abdominal aortic aneurysm repair (EVAR) in reducing inhospital mortality against open graft replace-ment for aortic aneurysm. Methods: Generic terms including EVAR, endovascular aneurysm repair and aorti...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2008-07-01
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| Series: | Asian Journal of Surgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1015958408600718 |
| _version_ | 1828758302102650880 |
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| author | Muhammad S. Sajid Mittal Desai Zishan Haider Daryll M. Baker George Hamilton |
| author_facet | Muhammad S. Sajid Mittal Desai Zishan Haider Daryll M. Baker George Hamilton |
| author_sort | Muhammad S. Sajid |
| collection | DOAJ |
| description | Objective: The objective of this meta-analysis was to evaluate the effectiveness of endovascular abdominal aortic aneurysm repair (EVAR) in reducing inhospital mortality against open graft replace-ment for aortic aneurysm.
Methods: Generic terms including EVAR, endovascular aneurysm repair and aortic endografting were used to search a variety of electronic databases. Based on selection criteria, decisions regarding inclusion and exclusion of primary studies were made.
Results: A total of three randomized controlled trials on 1,468 patients were included. In the EVAR group, 12 of 759 (1.5%) patients died, compared to 33 of 709 (4.6%) patients who died in the open surgery group. In both the fixed and random effect models, EVAR was associated with statistically significantly lower perioperative mortality when compared to open surgical repair of aortic aneurysm. The risk ratio of 0.33 indicates that mortality is 3.3 times more likely in the open surgery group compared to the EVAR group.
Conclusion: EVAR carries a threefold lower risk of perioperative death in comparison to open repair of abdominal aortic aneurysm. This early advantage must be offset against the increased need for later re-intervention and probable equivalence of long-term outcome. In older and high operative risk patients, EVAR should be the treatment of choice. |
| first_indexed | 2024-12-11T00:39:51Z |
| format | Article |
| id | doaj.art-db63e09428db4d52a24ba984eff7d264 |
| institution | Directory Open Access Journal |
| issn | 1015-9584 |
| language | English |
| last_indexed | 2024-12-11T00:39:51Z |
| publishDate | 2008-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Asian Journal of Surgery |
| spelling | doaj.art-db63e09428db4d52a24ba984eff7d2642022-12-22T01:26:59ZengElsevierAsian Journal of Surgery1015-95842008-07-0131311912310.1016/S1015-9584(08)60071-8Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic ReviewMuhammad S. SajidMittal DesaiZishan HaiderDaryll M. BakerGeorge HamiltonObjective: The objective of this meta-analysis was to evaluate the effectiveness of endovascular abdominal aortic aneurysm repair (EVAR) in reducing inhospital mortality against open graft replace-ment for aortic aneurysm. Methods: Generic terms including EVAR, endovascular aneurysm repair and aortic endografting were used to search a variety of electronic databases. Based on selection criteria, decisions regarding inclusion and exclusion of primary studies were made. Results: A total of three randomized controlled trials on 1,468 patients were included. In the EVAR group, 12 of 759 (1.5%) patients died, compared to 33 of 709 (4.6%) patients who died in the open surgery group. In both the fixed and random effect models, EVAR was associated with statistically significantly lower perioperative mortality when compared to open surgical repair of aortic aneurysm. The risk ratio of 0.33 indicates that mortality is 3.3 times more likely in the open surgery group compared to the EVAR group. Conclusion: EVAR carries a threefold lower risk of perioperative death in comparison to open repair of abdominal aortic aneurysm. This early advantage must be offset against the increased need for later re-intervention and probable equivalence of long-term outcome. In older and high operative risk patients, EVAR should be the treatment of choice.http://www.sciencedirect.com/science/article/pii/S1015958408600718aortic aneurysmendograftendovascular aneurysm repairEVAR |
| spellingShingle | Muhammad S. Sajid Mittal Desai Zishan Haider Daryll M. Baker George Hamilton Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic Review Asian Journal of Surgery aortic aneurysm endograft endovascular aneurysm repair EVAR |
| title | Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic Review |
| title_full | Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic Review |
| title_fullStr | Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic Review |
| title_full_unstemmed | Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic Review |
| title_short | Endovascular Aortic Aneurysm Repair (EVAR) Has Significantly Lower Perioperative Mortality in Comparison to Open Repair: A Systematic Review |
| title_sort | endovascular aortic aneurysm repair evar has significantly lower perioperative mortality in comparison to open repair a systematic review |
| topic | aortic aneurysm endograft endovascular aneurysm repair EVAR |
| url | http://www.sciencedirect.com/science/article/pii/S1015958408600718 |
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