Elucidation of lipid nanoparticle surface structure in mRNA vaccines

Elucidation of lipid nanoparticle surface structure in mRNA vaccines

Abstract Lipid nanoparticles (LNPs) have been used as a carrier for messenger RNA (mRNA) vaccines. Surface properties of LNPs are important to the stability and function of mRNA vaccines. Polyethylene-glycol (PEG) is a functional lipid at the surface of LNPs that improves colloidal stability, increa...

Full description

Bibliographic Details
Main Authors: Mingzhang Maple Wang, Caitlin N. Wappelhorst, Erika L. Jensen, Ying-Chih Thomas Chi, Jason C. Rouse, Qin Zou
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43898-x

Similar Items

Similar Items