Short-term high-fat diet alters the mouse brain magnetic resonance imaging parameters consistently with neuroinflammation on males and metabolic rearrangements on females. A pre-clinical study with an optimized selection of linear mixed-effects models

Short-term high-fat diet alters the mouse brain magnetic resonance imaging parameters consistently with neuroinflammation on males and metabolic rearrangements on females. A pre-clinical study with an optimized selection of linear mixed-effects models

IntroductionHigh-fat diet (HFD) consumption is known to trigger an inflammatory response in the brain that prompts the dysregulation of energy balance, leads to insulin and leptin resistance, and ultimately obesity. Obesity, at the same, has been related to cerebral magnetic resonance imaging (MRI)...

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Bibliographic Details
Main Authors: Basilio Willem Campillo, David Galguera, Sebastian Cerdan, Pilar López-Larrubia, Blanca Lizarbe
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Neuroscience
Subjects:
high-fat diet
sexual dimorphism
MRI
obesity
inflammation
brain
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2022.1025108/full

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