Incidence and patterns of <it>ALK</it> FISH abnormalities seen in a large unselected series of lung carcinomas

Incidence and patterns of <it>ALK</it> FISH abnormalities seen in a large unselected series of lung carcinomas

<p>Abstract</p> <p>Background</p> <p>Anaplastic lymphoma receptor tyrosine kinase (<it>ALK</it>) gene rearrangements have been reported in 2-13% of patients with non-small cell lung cancer (NSCLC). Patients with <it>ALK</it> rearrangements do not...

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Bibliographic Details
Main Authors: Dai Zunyan, Kelly JoAnn C, Meloni-Ehrig Aurelia, Slovak Marilyn L, Boles Debra, Christacos Nicole C, Bryke Christine R, Schonberg Steven A, Otani-Rosa Jennifer, Pan Qiulu, Ho Albert K, Sanders Heather R, Zhang Zhong J, Jones Dan, Mowrey Philip N
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Molecular Cytogenetics
Subjects:
<it>ALK</it> rearrangement
<it>ALK</it> amplification
FISH
<it>KRAS</it>
<it>EGFR</it>
Non-small cell lung cancer
Adenocarcinoma
Crizotinib
Online Access:http://www.molecularcytogenetics.org/content/5/1/44

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