Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case report
Abstract Background Bilateral diffuse uveal melanocytic proliferation (BDUMP) is an extremely rare paraneoplastic syndrome, with most cases reported as secondary to female urogenital and male lung malignancies. We reported this case of BDUMP patient whose primary malignancy was gastric adenocarcinom...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-03-01
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| Series: | BMC Ophthalmology |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12886-020-01376-2 |
| _version_ | 1818296924160131072 |
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| author | Mingyue Luo Zhe Chen Yaping Luo Lin Zhao Rongping Dai Yong Zhong |
| author_facet | Mingyue Luo Zhe Chen Yaping Luo Lin Zhao Rongping Dai Yong Zhong |
| author_sort | Mingyue Luo |
| collection | DOAJ |
| description | Abstract Background Bilateral diffuse uveal melanocytic proliferation (BDUMP) is an extremely rare paraneoplastic syndrome, with most cases reported as secondary to female urogenital and male lung malignancies. We reported this case of BDUMP patient whose primary malignancy was gastric adenocarcinoma verified with gastroscopy and subsequent pathological test. Case presentation A patient complaining blurred vision was suspected of bilateral diffuse uveal melanocytic proliferation (BDUMP), due to bilateral round oval patches at the posterior pole and cardinal signs in retinal angiography. Malignancy screening was suggested, and pathological report from gastroscopy confirmed the primary lesion as gastric adenocarcinoma. The patient chose palliative care due to late stage and unresectable nature of the malignancy. Conclusions Identifying BDUMP warrants further investigation of a primary malignancy. Our case provided evidence for the link between gastric adenocarcinoma and BDUMP. |
| first_indexed | 2024-12-13T04:11:16Z |
| format | Article |
| id | doaj.art-db6932679e73442fbe49261105a897c0 |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-12-13T04:11:16Z |
| publishDate | 2020-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Ophthalmology |
| spelling | doaj.art-db6932679e73442fbe49261105a897c02022-12-22T00:00:03ZengBMCBMC Ophthalmology1471-24152020-03-012011310.1186/s12886-020-01376-2Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case reportMingyue Luo0Zhe Chen1Yaping Luo2Lin Zhao3Rongping Dai4Yong Zhong5Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesDepartment of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical SciencesAbstract Background Bilateral diffuse uveal melanocytic proliferation (BDUMP) is an extremely rare paraneoplastic syndrome, with most cases reported as secondary to female urogenital and male lung malignancies. We reported this case of BDUMP patient whose primary malignancy was gastric adenocarcinoma verified with gastroscopy and subsequent pathological test. Case presentation A patient complaining blurred vision was suspected of bilateral diffuse uveal melanocytic proliferation (BDUMP), due to bilateral round oval patches at the posterior pole and cardinal signs in retinal angiography. Malignancy screening was suggested, and pathological report from gastroscopy confirmed the primary lesion as gastric adenocarcinoma. The patient chose palliative care due to late stage and unresectable nature of the malignancy. Conclusions Identifying BDUMP warrants further investigation of a primary malignancy. Our case provided evidence for the link between gastric adenocarcinoma and BDUMP.http://link.springer.com/article/10.1186/s12886-020-01376-2BDUMPGastric adenocarcinomaParaneoplastic syndrome |
| spellingShingle | Mingyue Luo Zhe Chen Yaping Luo Lin Zhao Rongping Dai Yong Zhong Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case report BMC Ophthalmology BDUMP Gastric adenocarcinoma Paraneoplastic syndrome |
| title | Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case report |
| title_full | Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case report |
| title_fullStr | Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case report |
| title_full_unstemmed | Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case report |
| title_short | Diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma: a case report |
| title_sort | diagnosis of bilateral diffuse uveal melanocytic proliferation unveils primary gastric adenocarcinoma a case report |
| topic | BDUMP Gastric adenocarcinoma Paraneoplastic syndrome |
| url | http://link.springer.com/article/10.1186/s12886-020-01376-2 |
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