Post operative analgesia after caesarean section: an experience with intrathecal buprenorphine
Buprenorphine is a mixed agonist-antagonist narcotic with high affinity at both µ and k opiate receptors. The aim of the study was to compare intrathecal bupivacaine (0.5%) and buprenorphine (60µg) with bupivacaine (0.5%) for postoperative analgesia in caesarean section. Sixty parturients undergoing...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2007-01-01
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| Series: | Indian Journal of Anaesthesia |
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| Online Access: | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2007;volume=51;issue=6;spage=515;epage=518;aulast=Dixit |
| _version_ | 1831789754766589952 |
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| author | Sunil Dixit |
| author_facet | Sunil Dixit |
| author_sort | Sunil Dixit |
| collection | DOAJ |
| description | Buprenorphine is a mixed agonist-antagonist narcotic with high affinity at both µ and k opiate receptors. The aim of the study was to compare intrathecal bupivacaine (0.5%) and buprenorphine (60µg) with bupivacaine (0.5%) for postoperative analgesia in caesarean section. Sixty parturients undergoing elective lower segment caesarean section (LSCS) were randomly selected after dividing into two groups of 30 each. Control group (C) received 1.70ml (8.5mg) of bupivacaine (0.5%) while patients of Study group (S) received 1.70ml (8.5mg) bupivacaine 0.5% + 60µg buprenorphine. Onset of analgesia was 5.35± 1.79 min in Control group, while 1.85 ± 1.39 min in Study group (P< 0.001). The total duration of analgesia was prolonged from145.16 ± 25.86 min in Control group to 491.26 ± 153.97min in Study group. We conclude that intrathecal buprenorphine is a suitable drug for postoperative analgesia after caesarean section with no effects on neonatal Apgar scores with minimal side effects. |
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| id | doaj.art-db6966f0df3d465a856d4a2456a423e2 |
| institution | Directory Open Access Journal |
| issn | 0019-5049 |
| language | English |
| last_indexed | 2024-12-22T14:16:44Z |
| publishDate | 2007-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Anaesthesia |
| spelling | doaj.art-db6966f0df3d465a856d4a2456a423e22022-12-21T18:23:05ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50492007-01-01516515518Post operative analgesia after caesarean section: an experience with intrathecal buprenorphineSunil DixitBuprenorphine is a mixed agonist-antagonist narcotic with high affinity at both µ and k opiate receptors. The aim of the study was to compare intrathecal bupivacaine (0.5%) and buprenorphine (60µg) with bupivacaine (0.5%) for postoperative analgesia in caesarean section. Sixty parturients undergoing elective lower segment caesarean section (LSCS) were randomly selected after dividing into two groups of 30 each. Control group (C) received 1.70ml (8.5mg) of bupivacaine (0.5%) while patients of Study group (S) received 1.70ml (8.5mg) bupivacaine 0.5% + 60µg buprenorphine. Onset of analgesia was 5.35± 1.79 min in Control group, while 1.85 ± 1.39 min in Study group (P< 0.001). The total duration of analgesia was prolonged from145.16 ± 25.86 min in Control group to 491.26 ± 153.97min in Study group. We conclude that intrathecal buprenorphine is a suitable drug for postoperative analgesia after caesarean section with no effects on neonatal Apgar scores with minimal side effects.http://www.ijaweb.org/article.asp?issn=0019-5049;year=2007;volume=51;issue=6;spage=515;epage=518;aulast=DixitBuprenorphineIntrathecal anaesthesia; Post-operative analgesia |
| spellingShingle | Sunil Dixit Post operative analgesia after caesarean section: an experience with intrathecal buprenorphine Indian Journal of Anaesthesia Buprenorphine Intrathecal anaesthesia; Post-operative analgesia |
| title | Post operative analgesia after caesarean section: an experience with intrathecal buprenorphine |
| title_full | Post operative analgesia after caesarean section: an experience with intrathecal buprenorphine |
| title_fullStr | Post operative analgesia after caesarean section: an experience with intrathecal buprenorphine |
| title_full_unstemmed | Post operative analgesia after caesarean section: an experience with intrathecal buprenorphine |
| title_short | Post operative analgesia after caesarean section: an experience with intrathecal buprenorphine |
| title_sort | post operative analgesia after caesarean section an experience with intrathecal buprenorphine |
| topic | Buprenorphine Intrathecal anaesthesia; Post-operative analgesia |
| url | http://www.ijaweb.org/article.asp?issn=0019-5049;year=2007;volume=51;issue=6;spage=515;epage=518;aulast=Dixit |
| work_keys_str_mv | AT sunildixit postoperativeanalgesiaaftercaesareansectionanexperiencewithintrathecalbuprenorphine |