APPLICATION OF INHIBITOR ANALYSIS FOR STUDYING MECHANISMS AND ACTIONS OF POLYMURAMYL, A MURAMYL PEPTIDE-BASED IMMUNE MODULATOR

APPLICATION OF INHIBITOR ANALYSIS FOR STUDYING MECHANISMS AND ACTIONS OF POLYMURAMYL, A MURAMYL PEPTIDE-BASED IMMUNE MODULATOR

In present study, the following low-MW inhibitors were used to dissect mechanisms of action for two muramyl peptide components of Polymuramyl, an immunomodulatory drug: (1) N-acetyl-D-glucosaminyl-(β1→4)-N-acetyl-D-muramoyl-L-alanyl-D-isoglutaminyl-meso-diaminopimelic acid (GMtri); (2) a dimeric   m...

Full description

Bibliographic Details
Main Authors: M. V. Pashenkov, B. I. Alkhazova, V. L. L'vov, B. V. Pinegin
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
muramyl peptides
macrophages
sb203580
genistein
tumor necrosis factor
Online Access:https://www.mimmun.ru/mimmun/article/view/59

Similar Items

Similar Items