Ceftazidime–Avibactam in Combination with Imipenem as Salvage Therapy for ST11 KPC-33-Producing <i>Klebsiella pneumoniae</i>
A 22-year-old man, after a hematopoietic stem cell transplant, suffered long-term pneumonia caused by <i>bla</i><sub>KPC-2</sub>-positive <i>K. pneumoniae</i> and <i>bla</i><sub>KPC-33-</sub>positive <i>K. pneumoniae</i> alterna...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-04-01
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| Series: | Antibiotics |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6382/11/5/604 |
| Summary: | A 22-year-old man, after a hematopoietic stem cell transplant, suffered long-term pneumonia caused by <i>bla</i><sub>KPC-2</sub>-positive <i>K. pneumoniae</i> and <i>bla</i><sub>KPC-33-</sub>positive <i>K. pneumoniae</i> alternately and finally achieved pathogenic clearance and improvement of clinical infectious conditions after using ceftazidime–avibactam in combination with imipenem as salvage therapy. This case provides a reference for treating infection caused by <i>K. pneumoniae</i> with a KPC variant in countries lacking new antimicrobial agents. |
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| ISSN: | 2079-6382 |