Combination of machine learning-based bulk and single-cell genomics reveals necroptosis-related molecular subtypes and immunological features in autism spectrum disorder

Combination of machine learning-based bulk and single-cell genomics reveals necroptosis-related molecular subtypes and immunological features in autism spectrum disorder

BackgroundNecroptosis is a novel form of controlled cell death that contributes to the progression of various illnesses. Nonetheless, the function and significance of necroptosis in autism spectrum disorders (ASD) remain unknown and require further investigation.MethodsWe utilized single-nucleus RNA...

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Bibliographic Details
Main Authors: Lichun Liu, Qingxian Fu, Huaili Ding, Hua Jiang, Zhidong Zhan, Yongxing Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Immunology
Subjects:
single-cell
autism spectrum disorder
necroptosis
molecular subtype
machine learning
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1139420/full

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