Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder
Alpha-band (8–12 Hz) event-related desynchronization (ERD) or a decrease in alpha power in electro- and magnetoencephalography (EEG and MEG) reflects the involvement of a neural tissue in information processing. It is known that most children with autism spectrum disorder (ASD) have difficulties in...
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MDPI AG
2023-09-01
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| Online Access: | https://www.mdpi.com/2076-3425/13/9/1313 |
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| author | Vardan Arutiunian Giorgio Arcara Irina Buyanova Olga Buivolova Elizaveta Davydova Darya Pereverzeva Alexander Sorokin Svetlana Tyushkevich Uliana Mamokhina Kamilla Danilina Olga Dragoy |
| author_facet | Vardan Arutiunian Giorgio Arcara Irina Buyanova Olga Buivolova Elizaveta Davydova Darya Pereverzeva Alexander Sorokin Svetlana Tyushkevich Uliana Mamokhina Kamilla Danilina Olga Dragoy |
| author_sort | Vardan Arutiunian |
| collection | DOAJ |
| description | Alpha-band (8–12 Hz) event-related desynchronization (ERD) or a decrease in alpha power in electro- and magnetoencephalography (EEG and MEG) reflects the involvement of a neural tissue in information processing. It is known that most children with autism spectrum disorder (ASD) have difficulties in information processing, and, thus, investigation of alpha oscillations is of particular interest in this population. Previous studies have demonstrated alterations in this neural activity in individuals with ASD; however, little is known about alpha ERD during simultaneous presentation of auditory and visual stimuli in children with and without ASD. As alpha oscillations are intimately related to attention, and attention deficit is one of the common co-occurring conditions of ASD, we predict that children with ASD can have altered alpha ERD in one of the sensory domains. In the present study, we used MEG to investigate alpha ERD in groups of 20 children with ASD and 20 age-matched typically developing controls. Simple amplitude-modulated tones were presented together with a fixation cross appearing on the screen. The results showed that children with ASD had a bilateral reduction in alpha-band ERD in the auditory but not visual cortex. Moreover, alterations in the auditory cortex were associated with a higher presence of autistic traits measured in behavioral assessment. |
| first_indexed | 2024-03-10T22:58:45Z |
| format | Article |
| id | doaj.art-db6ee7dd52704a6891061feade2b5217 |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-10T22:58:45Z |
| publishDate | 2023-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-db6ee7dd52704a6891061feade2b52172023-11-19T09:49:11ZengMDPI AGBrain Sciences2076-34252023-09-01139131310.3390/brainsci13091313Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum DisorderVardan Arutiunian0Giorgio Arcara1Irina Buyanova2Olga Buivolova3Elizaveta Davydova4Darya Pereverzeva5Alexander Sorokin6Svetlana Tyushkevich7Uliana Mamokhina8Kamilla Danilina9Olga Dragoy10Center for Child Health, Behavior and Development, Seattle Children’s Research Institute, 1920 Terry Ave., Seattle, WA 98101, USAIRCCS San Camillo Hospital, 70 Via Alberoni, Lido, 30126 Venice, ItalyCenter for Language and Brain, HSE University, 3 Krivokolenny Pereulok, 101000 Moscow, RussiaCenter for Language and Brain, HSE University, 3 Krivokolenny Pereulok, 101000 Moscow, RussiaFederal Resource Center for ASD, Moscow State University of Psychology and Education, 19 Architectora Vlasova Str., 117335 Moscow, RussiaFederal Resource Center for ASD, Moscow State University of Psychology and Education, 19 Architectora Vlasova Str., 117335 Moscow, RussiaFederal Resource Center for ASD, Moscow State University of Psychology and Education, 19 Architectora Vlasova Str., 117335 Moscow, RussiaFederal Resource Center for ASD, Moscow State University of Psychology and Education, 19 Architectora Vlasova Str., 117335 Moscow, RussiaFederal Resource Center for ASD, Moscow State University of Psychology and Education, 19 Architectora Vlasova Str., 117335 Moscow, RussiaFederal Resource Center for ASD, Moscow State University of Psychology and Education, 19 Architectora Vlasova Str., 117335 Moscow, RussiaCenter for Language and Brain, HSE University, 3 Krivokolenny Pereulok, 101000 Moscow, RussiaAlpha-band (8–12 Hz) event-related desynchronization (ERD) or a decrease in alpha power in electro- and magnetoencephalography (EEG and MEG) reflects the involvement of a neural tissue in information processing. It is known that most children with autism spectrum disorder (ASD) have difficulties in information processing, and, thus, investigation of alpha oscillations is of particular interest in this population. Previous studies have demonstrated alterations in this neural activity in individuals with ASD; however, little is known about alpha ERD during simultaneous presentation of auditory and visual stimuli in children with and without ASD. As alpha oscillations are intimately related to attention, and attention deficit is one of the common co-occurring conditions of ASD, we predict that children with ASD can have altered alpha ERD in one of the sensory domains. In the present study, we used MEG to investigate alpha ERD in groups of 20 children with ASD and 20 age-matched typically developing controls. Simple amplitude-modulated tones were presented together with a fixation cross appearing on the screen. The results showed that children with ASD had a bilateral reduction in alpha-band ERD in the auditory but not visual cortex. Moreover, alterations in the auditory cortex were associated with a higher presence of autistic traits measured in behavioral assessment.https://www.mdpi.com/2076-3425/13/9/1313autism spectrum disordermagnetoencephalographyauditory cortexevent-related desynchronization (ERD)alpha power |
| spellingShingle | Vardan Arutiunian Giorgio Arcara Irina Buyanova Olga Buivolova Elizaveta Davydova Darya Pereverzeva Alexander Sorokin Svetlana Tyushkevich Uliana Mamokhina Kamilla Danilina Olga Dragoy Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder Brain Sciences autism spectrum disorder magnetoencephalography auditory cortex event-related desynchronization (ERD) alpha power |
| title | Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder |
| title_full | Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder |
| title_fullStr | Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder |
| title_full_unstemmed | Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder |
| title_short | Event-Related Desynchronization of MEG Alpha-Band Oscillations during Simultaneous Presentation of Audio and Visual Stimuli in Children with Autism Spectrum Disorder |
| title_sort | event related desynchronization of meg alpha band oscillations during simultaneous presentation of audio and visual stimuli in children with autism spectrum disorder |
| topic | autism spectrum disorder magnetoencephalography auditory cortex event-related desynchronization (ERD) alpha power |
| url | https://www.mdpi.com/2076-3425/13/9/1313 |
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