The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder
Abstract Background Intrusive mental imagery is associated with anxiety and mood instability within bipolar disorder and therefore represents a novel treatment target. Imagery Based Emotion Regulation (IBER) is a brief structured psychological intervention developed to enable people to use the skill...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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SpringerOpen
2023-07-01
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| Series: | International Journal of Bipolar Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s40345-023-00305-8 |
| _version_ | 1827895386744815616 |
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| author | Craig Steel Kim Wright Guy M. Goodwin Judit Simon Nicola Morant Rod S. Taylor Michael Brown Susie Jennings Susie A. Hales Jemma Regan Michaela Sibsey Zoe Thomas Lynette Meredith Emily A. Holmes |
| author_facet | Craig Steel Kim Wright Guy M. Goodwin Judit Simon Nicola Morant Rod S. Taylor Michael Brown Susie Jennings Susie A. Hales Jemma Regan Michaela Sibsey Zoe Thomas Lynette Meredith Emily A. Holmes |
| author_sort | Craig Steel |
| collection | DOAJ |
| description | Abstract Background Intrusive mental imagery is associated with anxiety and mood instability within bipolar disorder and therefore represents a novel treatment target. Imagery Based Emotion Regulation (IBER) is a brief structured psychological intervention developed to enable people to use the skills required to regulate the emotional impact of these images. Methods Participants aged 18 and over with a diagnosis of bipolar disorder and at least a mild level of anxiety were randomly assigned (1:1) to receive IBER plus treatment as usual (IBER + TAU) or treatment as usual alone (TAU). IBER was delivered in up to 12 sessions overs 16 weeks. Clinical and health economic data were collected at baseline, end of treatment and 16-weeks follow-up. Objectives were to inform the recruitment process, timeline and sample size estimate for a definitive trial and to refine trial procedures. We also explored the impact on participant outcomes of anxiety, depression, mania, and mood stability at 16-weeks and 32-weeks follow-up. Results Fifty-seven (28: IBER + TAU, 27: TAU) participants from two sites were randomised, with 50 being recruited within the first 12 months. Forty-seven (82%) participants provided outcome data at 16 and 32-weeks follow-up. Thirty-five participants engaged in daily mood monitoring at the 32-week follow-up stage. Retention in IBER treatment was high with 27 (96%) attending ≥ 7 sessions. No study participants experienced a serious adverse event. Discussion The feasibility criteria of recruitment, outcome completion, and intervention retention were broadly achieved, indicating that imagery-focused interventions for bipolar disorder are worthy of further investigation. |
| first_indexed | 2024-03-12T22:20:14Z |
| format | Article |
| id | doaj.art-db788dac8f914f169ce43af424d1797a |
| institution | Directory Open Access Journal |
| issn | 2194-7511 |
| language | English |
| last_indexed | 2024-03-12T22:20:14Z |
| publishDate | 2023-07-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | International Journal of Bipolar Disorders |
| spelling | doaj.art-db788dac8f914f169ce43af424d1797a2023-07-23T11:04:09ZengSpringerOpenInternational Journal of Bipolar Disorders2194-75112023-07-0111111010.1186/s40345-023-00305-8The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorderCraig Steel0Kim Wright1Guy M. Goodwin2Judit Simon3Nicola Morant4Rod S. Taylor5Michael Brown6Susie Jennings7Susie A. Hales8Jemma Regan9Michaela Sibsey10Zoe Thomas11Lynette Meredith12Emily A. Holmes13Oxford Health NHS Foundation Trust and University of OxfordUniversity of ExeterUniversity of OxfordDepartment of Health Economics, Center for Public Health, Medical University of ViennaUniversity College LondonMRC/CSO Social and Public Health Sciences Unit and Robertson Centre for Biostatistics, University of GlasgowUniversity of CambridgeUniversity of ReadingOxford Health NHS Foundation Trust and University of OxfordDevon Partnership NHS TrustUniversity of ReadingUniversity of SurreyUniversity of East LondonDepartment of Psychology, Uppsala UniversityAbstract Background Intrusive mental imagery is associated with anxiety and mood instability within bipolar disorder and therefore represents a novel treatment target. Imagery Based Emotion Regulation (IBER) is a brief structured psychological intervention developed to enable people to use the skills required to regulate the emotional impact of these images. Methods Participants aged 18 and over with a diagnosis of bipolar disorder and at least a mild level of anxiety were randomly assigned (1:1) to receive IBER plus treatment as usual (IBER + TAU) or treatment as usual alone (TAU). IBER was delivered in up to 12 sessions overs 16 weeks. Clinical and health economic data were collected at baseline, end of treatment and 16-weeks follow-up. Objectives were to inform the recruitment process, timeline and sample size estimate for a definitive trial and to refine trial procedures. We also explored the impact on participant outcomes of anxiety, depression, mania, and mood stability at 16-weeks and 32-weeks follow-up. Results Fifty-seven (28: IBER + TAU, 27: TAU) participants from two sites were randomised, with 50 being recruited within the first 12 months. Forty-seven (82%) participants provided outcome data at 16 and 32-weeks follow-up. Thirty-five participants engaged in daily mood monitoring at the 32-week follow-up stage. Retention in IBER treatment was high with 27 (96%) attending ≥ 7 sessions. No study participants experienced a serious adverse event. Discussion The feasibility criteria of recruitment, outcome completion, and intervention retention were broadly achieved, indicating that imagery-focused interventions for bipolar disorder are worthy of further investigation.https://doi.org/10.1186/s40345-023-00305-8Bipolar disorderAnxietyEmotion regulationMental imageryPsychological interventionFeasibility |
| spellingShingle | Craig Steel Kim Wright Guy M. Goodwin Judit Simon Nicola Morant Rod S. Taylor Michael Brown Susie Jennings Susie A. Hales Jemma Regan Michaela Sibsey Zoe Thomas Lynette Meredith Emily A. Holmes The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder International Journal of Bipolar Disorders Bipolar disorder Anxiety Emotion regulation Mental imagery Psychological intervention Feasibility |
| title | The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder |
| title_full | The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder |
| title_fullStr | The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder |
| title_full_unstemmed | The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder |
| title_short | The IBER study: a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder |
| title_sort | iber study a feasibility randomised controlled trial of imagery based emotion regulation for the treatment of anxiety in bipolar disorder |
| topic | Bipolar disorder Anxiety Emotion regulation Mental imagery Psychological intervention Feasibility |
| url | https://doi.org/10.1186/s40345-023-00305-8 |
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