Novel therapeutics in myeloproliferative neoplasms

Novel therapeutics in myeloproliferative neoplasms

Abstract Hyperactive signaling of the Janus-Associated Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) pathway is central to the pathogenesis of Philadelphia-chromosome-negative myeloproliferative neoplasms (MPN), i.e., polycythemia vera (PV), essential thrombocythemia (ET), and...

Bibliográfalaš dieđut
Váldodahkkit:	Sangeetha Venugopal, John Mascarenhas
Materiálatiipa:	Artihkal
Giella:	English
Almmustuhtton:	BMC 2020-12-01
Ráidu:	Journal of Hematology & Oncology
Fáttát:	MF ET PV JAK-STAT CALR Ruxolitinib
Liŋkkat:	https://doi.org/10.1186/s13045-020-00995-y

Geahča maid

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Insights from a rare myeloproliferative neoplasm with coexisting BCR‐ABL1 fusion gene, CALR, and TET2 mutations treated with nilotinib and ruxolitinib
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Corrigendum: Patients with myeloproliferative neoplasms harbor high frequencies of CD8 T cell-platelet aggregates associated with T cell suppression
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