Novel therapeutics in myeloproliferative neoplasms

Abstract Hyperactive signaling of the Janus-Associated Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) pathway is central to the pathogenesis of Philadelphia-chromosome-negative myeloproliferative neoplasms (MPN), i.e., polycythemia vera (PV), essential thrombocythemia (ET), and...

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Autori principali: Sangeetha Venugopal, John Mascarenhas
Natura: Articolo
Lingua:English
Pubblicazione: BMC 2020-12-01
Serie:Journal of Hematology & Oncology
Soggetti:
Accesso online:https://doi.org/10.1186/s13045-020-00995-y