The Transcriptional Effects of PCB118 and PCB153 on the Liver, Adipose Tissue, Muscle and Colon of Mice: Highlighting of Glut4 and Lipin1 as Main Target Genes for PCB Induced Metabolic Disorders.

The Transcriptional Effects of PCB118 and PCB153 on the Liver, Adipose Tissue, Muscle and Colon of Mice: Highlighting of Glut4 and Lipin1 as Main Target Genes for PCB Induced Metabolic Disorders.

Epidemiological studies have associated environmental exposure to polychlorinated biphenyls (PCBs) with an increased risk of type 2 diabetes; however, little is known about the underlying mechanisms involved in the metabolic side-effects of PCB. Our study evaluated the transcriptional effects of a s...

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Main Authors: Aurélia Mesnier, Serge Champion, Laurence Louis, Christophe Sauzet, Phealay May, Henri Portugal, Karim Benbrahim, Joelle Abraldes, Marie-Christine Alessi, Marie-Josephe Amiot-Carlin, Franck Peiretti, Philippe Piccerelle, Gilles Nalbone, Pierre-Henri Villard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4473719?pdf=render

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