Natural Clearance of Prolonged VDPV Infection in a Child With Primary Immunodeficiency Disorder

Natural Clearance of Prolonged VDPV Infection in a Child With Primary Immunodeficiency Disorder

The emergence of immunodeficiency-associated vaccine-derived polioviruses (iVDPV) from children with primary immunodeficiency disorders poses a threat to the eradication program. Herein, we report a patient with severe combined immunodeficiency (SCID), identified as a prolonged serotype 3 iVDPV (iVD...

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Bibliographic Details
Main Authors: Madhu Chhanda Mohanty, Manisha Ranjan Madkaikar, Mukesh Desai, Jahnavi Aluri, Swapnil Yashwant Varose, Prasad Taur, Deepa Kailash Sharma, Uma Prajwal Nalavade, Sneha Vijay Rane, Maya Gupta, Snehal Shabarish, Aparna Dalvi, Jagadish Mohanrao Deshpande
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
primary immunodeficiency disorder
oral polio vaccine
vaccine-derived polioviruses
severe combined immune-deficiency
leaky SCID
inflammatory cytokines
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01567/full

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