Sex differences in obstructive sleep apnoea

Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have long been considered predominantly male-related conditions. The clinical presentation of sleep disordered breathing in females differs from males and can vary with age and physiological status, e.g. menopause...

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Xehetasun bibliografikoak
Egile Nagusiak: Maria R. Bonsignore, Tarja Saaresranta, Renata L. Riha
Formatua: Artikulua
Hizkuntza:English
Argitaratua: European Respiratory Society 2019-11-01
Saila:European Respiratory Review
Sarrera elektronikoa:http://err.ersjournals.com/content/28/154/190030.full
Deskribapena
Gaia:Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have long been considered predominantly male-related conditions. The clinical presentation of sleep disordered breathing in females differs from males and can vary with age and physiological status, e.g. menopause and pregnancy. Overall, females appear to be more symptomatic, with lower apnoea–hypopnoea index scores compared to males. Furthermore, they appear to have more prolonged partial upper airway obstruction, and may report insomnia as a symptom of OSAHS more frequently. As a consequence of these differences in clinical presentation, females with sleep disordered breathing are often underdiagnosed and undertreated compared to males. This review is aimed at discussing the epidemiology, clinical presentation, pathophysiology and hormonal and metabolic differences in females who present with OSA/OSAHS in comparison to males.
ISSN:0905-9180
1600-0617